CAPNS2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CAPNS2 at tissue level.

III. Associated gene sets

GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0110158Cellular componentcalpain complex
GO_0004198Molecular functioncalcium-dependent cysteine-type endopeptidase activity
GO_0005509Molecular functioncalcium ion binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCAPNS2
Protein nameCalpain small subunit 2 (CSS2) (Calcium-dependent protease small subunit 2)
Synonyms
DescriptionFUNCTION: Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. This small subunit may act as a tissue-specific chaperone of the large subunit, possibly by helping it fold into its correct conformation for activity.

AccessionsQ96L46
ENST00000457326.3