Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| type II pneumocyte | 6 studies | 40% ± 7% | |
| respiratory goblet cell | 5 studies | 43% ± 17% | |
| goblet cell | 5 studies | 38% ± 22% | |
| club cell | 5 studies | 34% ± 13% | |
| mucus secreting cell | 3 studies | 26% ± 10% |
Insufficient scRNA-seq data for expression of CAPN8 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| stomach | 83% | 6957.16 | 297 / 359 | 85% | 30.10 | 244 / 286 |
| lung | 98% | 2243.37 | 565 / 578 | 63% | 35.04 | 727 / 1155 |
| intestine | 56% | 1137.17 | 541 / 966 | 91% | 33.30 | 482 / 527 |
| pancreas | 59% | 282.18 | 194 / 328 | 87% | 85.94 | 154 / 178 |
| breast | 74% | 1085.28 | 338 / 459 | 65% | 29.51 | 732 / 1118 |
| bladder | 86% | 1982.48 | 18 / 21 | 51% | 17.25 | 257 / 504 |
| ureter | 0% | 0 | 0 / 0 | 100% | 12.61 | 1 / 1 |
| prostate | 86% | 607.09 | 210 / 245 | 3% | 0.35 | 17 / 502 |
| kidney | 76% | 334.82 | 68 / 89 | 2% | 0.47 | 17 / 901 |
| esophagus | 13% | 39.42 | 190 / 1445 | 43% | 23.96 | 79 / 183 |
| skin | 52% | 207.52 | 934 / 1809 | 1% | 0.04 | 3 / 472 |
| muscle | 40% | 68.13 | 322 / 803 | 0% | 0 | 0 / 0 |
| uterus | 8% | 24.05 | 13 / 170 | 21% | 8.09 | 95 / 459 |
| liver | 15% | 21.53 | 33 / 226 | 5% | 1.64 | 21 / 406 |
| ovary | 12% | 18.51 | 21 / 180 | 6% | 0.57 | 26 / 430 |
| adrenal gland | 13% | 32.71 | 33 / 258 | 1% | 0.07 | 2 / 230 |
| thymus | 8% | 8.60 | 53 / 653 | 2% | 0.29 | 11 / 605 |
| brain | 9% | 9.00 | 233 / 2642 | 0% | 0 | 0 / 705 |
| adipose | 7% | 13.26 | 90 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.52 | 1 / 45 |
| blood vessel | 1% | 0.91 | 10 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 1% | 1.62 | 6 / 929 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0.30 | 1 / 241 | 0% | 0 | 0 / 0 |
| heart | 0% | 0.71 | 3 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006508 | Biological process | proteolysis |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0004198 | Molecular function | calcium-dependent cysteine-type endopeptidase activity |
| GO_0005509 | Molecular function | calcium ion binding |
| Gene name | CAPN8 |
| Protein name | Calpain 8 (HCG2036808, isoform CRA_a) Calpain 8 Calpain-8 (EC 3.4.22.53) (New calpain 2) (nCL-2) (Stomach-specific M-type calpain) |
| Synonyms | NCL2 hCG_2036808 |
| Description | FUNCTION: Calcium-regulated non-lysosomal thiol-protease. Involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein. Proteolytically cleaves the beta-subunit of coatomer complex (By similarity). . |
| Accessions | ENST00000366873.6 H0YEQ4 A3QK36 ENST00000465098.1 H0YEJ4 ENST00000484873.6 ENST00000442247.5 A6NHC0 ENST00000467384.6 B1B154 H0YDN4 ENST00000366872.10 |
