I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| extravillous trophoblast | 3 studies | 22% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| extravillous trophoblast | 3 studies | 22% ± 5% |
Insufficient scRNA-seq data for expression of CAPN6 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 99% | 411.30 | 324 / 328 | 77% | 17.07 | 137 / 178 |
| stomach | 99% | 958.29 | 357 / 359 | 54% | 25.42 | 154 / 286 |
| prostate | 94% | 679.65 | 231 / 245 | 46% | 5.34 | 230 / 502 |
| ovary | 95% | 330.33 | 171 / 180 | 39% | 13.87 | 168 / 430 |
| kidney | 81% | 604.52 | 72 / 89 | 52% | 27.30 | 468 / 901 |
| intestine | 87% | 582.70 | 838 / 966 | 45% | 14.84 | 239 / 527 |
| uterus | 98% | 2021.72 | 167 / 170 | 29% | 44.52 | 135 / 459 |
| breast | 88% | 1021.15 | 405 / 459 | 31% | 15.46 | 345 / 1118 |
| esophagus | 78% | 382.38 | 1128 / 1445 | 32% | 11.11 | 58 / 183 |
| thymus | 83% | 288.63 | 545 / 653 | 15% | 2.91 | 91 / 605 |
| blood vessel | 63% | 184.97 | 844 / 1335 | 0% | 0 | 0 / 0 |
| bladder | 43% | 238.00 | 9 / 21 | 18% | 6.11 | 92 / 504 |
| adipose | 57% | 225.51 | 685 / 1204 | 0% | 0 | 0 / 0 |
| skin | 42% | 104.77 | 763 / 1809 | 6% | 1.42 | 27 / 472 |
| muscle | 44% | 177.29 | 352 / 803 | 0% | 0 | 0 / 0 |
| lung | 11% | 14.97 | 65 / 578 | 25% | 10.97 | 293 / 1155 |
| spleen | 34% | 52.19 | 81 / 241 | 0% | 0 | 0 / 0 |
| liver | 7% | 11.43 | 16 / 226 | 16% | 8.09 | 66 / 406 |
| heart | 10% | 19.02 | 87 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 7% | 0.87 | 2 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 7% | 0.41 | 3 / 45 |
| adrenal gland | 1% | 2.14 | 3 / 258 | 4% | 1.79 | 9 / 230 |
| brain | 0% | 0.56 | 7 / 2642 | 3% | 2.94 | 18 / 705 |
| eye | 0% | 0 | 0 / 0 | 3% | 0.15 | 2 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006508 | Biological process | proteolysis |
| GO_0001578 | Biological process | microtubule bundle formation |
| GO_0051493 | Biological process | regulation of cytoskeleton organization |
| GO_0005876 | Cellular component | spindle microtubule |
| GO_0048471 | Cellular component | perinuclear region of cytoplasm |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0004198 | Molecular function | calcium-dependent cysteine-type endopeptidase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0008017 | Molecular function | microtubule binding |
| Gene name | CAPN6 |
| Protein name | Calpain-6 (Calpain-like protease X-linked) (Calpamodulin) (CalpM) |
| Synonyms | CALPM CANPX |
| Description | FUNCTION: Microtubule-stabilizing protein that may be involved in the regulation of microtubule dynamics and cytoskeletal organization. May act as a regulator of RAC1 activity through interaction with ARHGEF2 to control lamellipodial formation and cell mobility. Does not seem to have protease activity as it has lost the active site residues (By similarity). . |
| Accessions | ENST00000324068.2 Q9Y6Q1 |
