I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 7 studies | 39% ± 21% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 7 studies | 39% ± 21% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 34% ± 16% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 99% | 1430.04 | 648 / 653 | 100% | 14.17 | 603 / 605 |
| uterus | 100% | 2547.02 | 170 / 170 | 96% | 8.89 | 441 / 459 |
| prostate | 98% | 1509.41 | 240 / 245 | 96% | 6.25 | 484 / 502 |
| adrenal gland | 98% | 1739.67 | 254 / 258 | 94% | 17.85 | 217 / 230 |
| pancreas | 95% | 1155.66 | 312 / 328 | 96% | 5.55 | 170 / 178 |
| brain | 93% | 6256.28 | 2466 / 2642 | 97% | 14.40 | 683 / 705 |
| bladder | 100% | 2854.48 | 21 / 21 | 88% | 5.06 | 442 / 504 |
| intestine | 97% | 1434.75 | 933 / 966 | 91% | 5.99 | 477 / 527 |
| breast | 90% | 975.21 | 413 / 459 | 94% | 6.27 | 1047 / 1118 |
| esophagus | 92% | 1073.29 | 1331 / 1445 | 91% | 6.05 | 167 / 183 |
| skin | 95% | 2058.61 | 1713 / 1809 | 83% | 4.07 | 391 / 472 |
| lung | 84% | 884.97 | 484 / 578 | 90% | 5.59 | 1039 / 1155 |
| ovary | 98% | 1334.85 | 177 / 180 | 57% | 2.33 | 244 / 430 |
| kidney | 47% | 365.25 | 42 / 89 | 90% | 6.36 | 813 / 901 |
| stomach | 46% | 434.92 | 165 / 359 | 83% | 4.83 | 237 / 286 |
| spleen | 100% | 1654.37 | 240 / 241 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 91% | 5.50 | 73 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 91% | 8.97 | 41 / 45 |
| adipose | 90% | 1040.83 | 1078 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 84% | 1654.23 | 1125 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 79% | 1844.23 | 733 / 929 | 0% | 0 | 0 / 0 |
| heart | 47% | 373.69 | 401 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 31% | 0.83 | 9 / 29 |
| muscle | 19% | 152.34 | 152 / 803 | 0% | 0 | 0 / 0 |
| liver | 0% | 5.07 | 1 / 226 | 8% | 0.39 | 32 / 406 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0035556 | Biological process | intracellular signal transduction |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0004683 | Molecular function | calmodulin-dependent protein kinase activity |
| GO_0005516 | Molecular function | calmodulin binding |
| GO_0106310 | Molecular function | protein serine kinase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0005524 | Molecular function | ATP binding |
| Gene name | CAMKK1 |
| Protein name | Calcium/calmodulin dependent protein kinase kinase 1 Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) (CaMKK 1) (EC 2.7.11.17) (CaM-kinase IV kinase) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-KK alpha) (CaM-kinase kinase alpha) (CaMKK alpha) |
| Synonyms | CAMKKA |
| Description | FUNCTION: Calcium/calmodulin-dependent protein kinase that belongs to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Phosphorylates CAMK1, CAMK1D, CAMK1G and CAMK4. Involved in regulating cell apoptosis. Promotes cell survival by phosphorylating AKT1/PKB that inhibits pro-apoptotic BAD/Bcl2-antagonist of cell death. . |
| Accessions | J3KPJ3 ENST00000381769.6 ENST00000348335.7 [Q8N5S9-1] ENST00000158166.5 [Q8N5S9-2] Q8N5S9 |
