Insufficient scRNA-seq data for expression of CACNA1H at tissue level.
Tissue | GTEx Coverage  | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 98% | 12480.71 | 241 / 245 | 98% | 31.16 | 490 / 502 |
| adrenal gland | 97% | 10720.71 | 251 / 258 | 77% | 31.96 | 178 / 230 |
| intestine | 90% | 24604.22 | 865 / 966 | 74% | 8.11 | 391 / 527 |
| bladder | 100% | 22008.95 | 21 / 21 | 53% | 5.63 | 268 / 504 |
| esophagus | 76% | 21721.61 | 1101 / 1445 | 76% | 11.94 | 139 / 183 |
| stomach | 59% | 8756.24 | 212 / 359 | 81% | 13.55 | 233 / 286 |
| thymus | 88% | 4442.94 | 575 / 653 | 52% | 3.83 | 314 / 605 |
| ovary | 100% | 29172.09 | 180 / 180 | 34% | 3.29 | 145 / 430 |
| kidney | 63% | 2970.57 | 56 / 89 | 66% | 8.78 | 591 / 901 |
| uterus | 99% | 18950.88 | 168 / 170 | 29% | 6.35 | 132 / 459 |
| lung | 87% | 4360.48 | 500 / 578 | 38% | 6.24 | 444 / 1155 |
| breast | 58% | 2791.07 | 264 / 459 | 59% | 16.82 | 659 / 1118 |
| brain | 33% | 1915.05 | 867 / 2642 | 70% | 6.31 | 492 / 705 |
| ureter | 0% | 0 | 0 / 0 | 100% | 28.48 | 1 / 1 |
| pancreas | 5% | 149.59 | 15 / 328 | 94% | 15.84 | 167 / 178 |
| liver | 45% | 2567.79 | 102 / 226 | 48% | 12.47 | 194 / 406 |
| blood vessel | 83% | 12595.89 | 1108 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 78% | 4375.83 | 942 / 1204 | 0% | 0 | 0 / 0 |
| skin | 51% | 3857.07 | 929 / 1809 | 22% | 2.85 | 104 / 472 |
| eye | 0% | 0 | 0 / 0 | 65% | 10.84 | 52 / 80 |
| heart | 24% | 769.62 | 208 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 13% | 0.63 | 6 / 45 |
| muscle | 7% | 268.60 | 58 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| GO_0035865 | Biological process | cellular response to potassium ion |
| GO_0042391 | Biological process | regulation of membrane potential |
| GO_2000344 | Biological process | positive regulation of acrosome reaction |
| GO_0098703 | Biological process | calcium ion import across plasma membrane |
| GO_0032870 | Biological process | cellular response to hormone stimulus |
| GO_0006936 | Biological process | muscle contraction |
| GO_0098662 | Biological process | inorganic cation transmembrane transport |
| GO_0070509 | Biological process | calcium ion import |
| GO_0034651 | Biological process | cortisol biosynthetic process |
| GO_0007517 | Biological process | muscle organ development |
| GO_0007520 | Biological process | myoblast fusion |
| GO_0032342 | Biological process | aldosterone biosynthetic process |
| GO_0008016 | Biological process | regulation of heart contraction |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0005891 | Cellular component | voltage-gated calcium channel complex |
| GO_0005244 | Molecular function | voltage-gated monoatomic ion channel activity |
| GO_0097110 | Molecular function | scaffold protein binding |
| GO_0008332 | Molecular function | low voltage-gated calcium channel activity |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0008331 | Molecular function | high voltage-gated calcium channel activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | CACNA1H |
| Protein name | Low-voltage-activated calcium channel alpha1H subunit splice variant 513 Low-voltage-activated calcium channel alpha1H subunit splice variant 512 Calcium voltage-gated channel subunit alpha1 H Voltage-dependent T-type calcium channel subunit alpha-1H (Low-voltage-activated calcium channel alpha1 3.2 subunit) (Voltage-gated calcium channel subunit alpha Cav3.2) Low-voltage-activated calcium channel alpha13.2 subunit Low-voltage-activated calcium channel alpha1H subunit splice variant 577 Low-voltage-activated calcium channel alpha1H subunit splice variant 544 |
| Synonyms | |
| Description | FUNCTION: Voltage-sensitive calcium channel that gives rise to T-type calcium currents. T-type calcium channels belong to the 'low-voltage activated (LVA)' group. A particularity of this type of channel is an opening at quite negative potentials, and a voltage-dependent inactivation . T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle (Probable). They may also be involved in the modulation of firing patterns of neurons . In the adrenal zona glomerulosa, participates in the signaling pathway leading to aldosterone production in response to either AGT/angiotensin II, or hyperkalemia . . |
| Accessions | ENST00000348261.11 [O95180-1] A0A1W2PR14 O95180 A0A1W2PQW2 ENST00000569107.5 A2SX37 A0A1W2PQ19 A2SX38 H3BMW6 ENST00000562079.5 ENST00000358590.8 [O95180-2] ENST00000564231.5 H3BNT0 Q9NYY6 ENST00000638323.1 H3BUA8 Q9NYY7 ENST00000639478.1 A0A1W2PS38 A2SX36 ENST00000640028.1 ENST00000565831.6 [O95180-2] ENST00000637236.2 A2SX35 |
