CABP1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007601Biological processvisual perception
GO_0042308Biological processnegative regulation of protein import into nucleus
GO_0005615Cellular componentextracellular space
GO_0000139Cellular componentGolgi membrane
GO_0005856Cellular componentcytoskeleton
GO_0005938Cellular componentcell cortex
GO_0005886Cellular componentplasma membrane
GO_0014069Cellular componentpostsynaptic density
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0005737Cellular componentcytoplasm
GO_0008139Molecular functionnuclear localization sequence binding
GO_0005246Molecular functioncalcium channel regulator activity
GO_0048306Molecular functioncalcium-dependent protein binding
GO_0004857Molecular functionenzyme inhibitor activity
GO_0005509Molecular functioncalcium ion binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCABP1
Protein nameCalcium-binding protein 1 (CaBP1) (Calbrain) (Caldendrin)
Calcium binding protein 1
Synonyms
DescriptionFUNCTION: Modulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors (ITPRs). Inhibits agonist-induced intracellular calcium signaling . Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels . Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but has an opposite effect on channel function . Suppresses the calcium-dependent inactivation of CACNA1D (By similarity). Inhibits TRPC5 channels . Prevents NMDA receptor-induced cellular degeneration. Required for the normal transfer of light signals through the retina (By similarity). .

AccessionsC9J8G2
ENST00000351200.6 [Q9NZU7-2]
Q9NZU7
ENST00000453000.1
ENST00000316803.8 [Q9NZU7-4]
ENST00000288616.7 [Q9NZU7-1]