I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| astrocyte | 3 studies | 34% ± 16% | |
| glutamatergic neuron | 3 studies | 29% ± 10% | |
| oligodendrocyte | 3 studies | 25% ± 9% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| astrocyte | 3 studies | 34% ± 16% | |
| glutamatergic neuron | 3 studies | 29% ± 10% | |
| oligodendrocyte | 3 studies | 25% ± 9% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 24% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| skin | 81% | 45.40 | 1465 / 1809 | 52% | 1.33 | 247 / 472 |
| ovary | 100% | 85.38 | 180 / 180 | 31% | 0.57 | 134 / 430 |
| lung | 96% | 52.10 | 555 / 578 | 33% | 0.84 | 383 / 1155 |
| adrenal gland | 100% | 118.47 | 257 / 258 | 27% | 0.58 | 61 / 230 |
| uterus | 98% | 46.82 | 167 / 170 | 13% | 0.27 | 58 / 459 |
| bladder | 90% | 30.76 | 19 / 21 | 14% | 0.29 | 69 / 504 |
| thymus | 95% | 38.83 | 621 / 653 | 8% | 0.15 | 51 / 605 |
| breast | 97% | 51.01 | 444 / 459 | 6% | 0.15 | 68 / 1118 |
| prostate | 98% | 44.27 | 240 / 245 | 2% | 0.03 | 9 / 502 |
| blood vessel | 96% | 55.28 | 1279 / 1335 | 0% | 0 | 0 / 0 |
| heart | 95% | 83.79 | 822 / 861 | 0% | 0 | 0 / 0 |
| intestine | 94% | 32.64 | 906 / 966 | 2% | 0.02 | 8 / 527 |
| adipose | 93% | 41.73 | 1124 / 1204 | 0% | 0 | 0 / 0 |
| brain | 92% | 36.85 | 2431 / 2642 | 1% | 0.02 | 7 / 705 |
| esophagus | 81% | 27.82 | 1170 / 1445 | 9% | 0.17 | 16 / 183 |
| kidney | 81% | 24.39 | 72 / 89 | 7% | 0.13 | 65 / 901 |
| spleen | 68% | 16.61 | 165 / 241 | 0% | 0 | 0 / 0 |
| liver | 56% | 13.11 | 126 / 226 | 4% | 0.07 | 16 / 406 |
| muscle | 58% | 15.05 | 468 / 803 | 0% | 0 | 0 / 0 |
| stomach | 48% | 13.27 | 172 / 359 | 3% | 0.06 | 9 / 286 |
| pancreas | 44% | 8.14 | 145 / 328 | 3% | 0.04 | 5 / 178 |
| eye | 0% | 0 | 0 / 0 | 26% | 0.46 | 21 / 80 |
| peripheral blood | 3% | 0.43 | 30 / 929 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.03 | 1 / 45 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007283 | Biological process | spermatogenesis |
| GO_0030317 | Biological process | flagellated sperm motility |
| GO_0048240 | Biological process | sperm capacitation |
| GO_0098876 | Biological process | vesicle-mediated transport to the plasma membrane |
| GO_0097228 | Cellular component | sperm principal piece |
| GO_0036128 | Cellular component | CatSper complex |
| GO_0005515 | Molecular function | protein binding |
| Gene name | C2CD6 |
| Protein name | Cation channel sperm-associated targeting subunit tau (CatSper-tau) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein) (C2 calcium-dependent domain-containing protein 6) ALS2CR11 protein |
| Synonyms | ALS2CR11 CATSPERT |
| Description | FUNCTION: Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization. Required for CatSper complex targeting and trafficking into the quadrilinear nanodomains. Targets the preassembled CatSper complexes to elongating flagella, where it links the channel-carrying vesicles and motor proteins. . |
| Accessions | Q53TS8 Q96Q36 ENST00000439140.6 [Q53TS8-4] ENST00000286195.7 [Q53TS8-1] ENST00000439802.5 [Q53TS8-2] ENST00000450242.1 [Q53TS8-3] |
