BTBD1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0016567Biological processprotein ubiquitination
GO_0022008Biological processneurogenesis
GO_0043393Biological processregulation of protein binding
GO_0007517Biological processmuscle organ development
GO_0000932Cellular componentP-body
GO_0032991Cellular componentprotein-containing complex
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0036464Cellular componentcytoplasmic ribonucleoprotein granule
GO_0042802Molecular functionidentical protein binding
GO_0097602Molecular functioncullin family protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameBTBD1
Protein nameBTB/POZ domain-containing protein 1 (Hepatitis C virus NS5A-transactivated protein 8) (HCV NS5A-transactivated protein 8)
BTB domain containing 1
SynonymsNS5ATP8
C15orf1
DescriptionFUNCTION: Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins . Seems to regulate expression levels and/or subnuclear distribution of TOP1, via an unknown mechanism (By similarity). May play a role in mesenchymal differentiation where it promotes myogenic differentiation and suppresses adipogenesis (By similarity). .

AccessionsQ9H0C5
ENST00000559652.5
H0YL89
ENST00000261721.9 [Q9H0C5-1]
Q3ZTS5
ENST00000379403.2 [Q9H0C5-2]