Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| oligodendrocyte | 7 studies | 23% ± 7% | |
| endothelial cell | 6 studies | 22% ± 8% | |
| epithelial cell | 4 studies | 23% ± 5% | |
| astrocyte | 4 studies | 21% ± 3% | |
| glutamatergic neuron | 4 studies | 38% ± 16% | |
| microglial cell | 3 studies | 17% ± 2% | |
| ciliated cell | 3 studies | 25% ± 3% | |
| GABAergic neuron | 3 studies | 39% ± 11% | |
| neuron | 3 studies | 24% ± 8% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 5 studies | 32% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 3471.54 | 2641 / 2642 | 100% | 15.92 | 705 / 705 |
| thymus | 100% | 2759.55 | 653 / 653 | 100% | 9.76 | 604 / 605 |
| prostate | 100% | 3211.07 | 245 / 245 | 100% | 12.38 | 501 / 502 |
| uterus | 100% | 2912.05 | 170 / 170 | 100% | 10.98 | 458 / 459 |
| breast | 100% | 2593.68 | 459 / 459 | 100% | 10.76 | 1113 / 1118 |
| esophagus | 100% | 2182.90 | 1445 / 1445 | 99% | 8.63 | 182 / 183 |
| pancreas | 100% | 1775.99 | 328 / 328 | 99% | 7.99 | 177 / 178 |
| intestine | 100% | 2279.36 | 966 / 966 | 99% | 7.95 | 524 / 527 |
| skin | 100% | 2380.25 | 1809 / 1809 | 99% | 10.68 | 469 / 472 |
| ovary | 100% | 2796.53 | 180 / 180 | 99% | 8.93 | 427 / 430 |
| stomach | 100% | 1814.26 | 359 / 359 | 99% | 7.46 | 284 / 286 |
| kidney | 100% | 2172.64 | 89 / 89 | 99% | 7.02 | 894 / 901 |
| bladder | 100% | 2515.95 | 21 / 21 | 99% | 9.68 | 500 / 504 |
| lung | 100% | 2213.17 | 577 / 578 | 99% | 9.07 | 1147 / 1155 |
| adrenal gland | 100% | 2182.40 | 258 / 258 | 99% | 11.80 | 227 / 230 |
| liver | 100% | 1535.69 | 226 / 226 | 97% | 5.32 | 395 / 406 |
| adipose | 100% | 2291.15 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 8.52 | 29 / 29 |
| spleen | 100% | 3076.89 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 7.81 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 10.72 | 1 / 1 |
| muscle | 100% | 1717.80 | 802 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1755.25 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| heart | 99% | 1356.64 | 854 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 99% | 11.87 | 79 / 80 |
| peripheral blood | 90% | 1194.70 | 834 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006384 | Biological process | transcription initiation at RNA polymerase III promoter |
| GO_0070897 | Biological process | transcription preinitiation complex assembly |
| GO_0045945 | Biological process | positive regulation of transcription by RNA polymerase III |
| GO_0009304 | Biological process | tRNA transcription |
| GO_0009303 | Biological process | rRNA transcription |
| GO_0006352 | Biological process | DNA-templated transcription initiation |
| GO_0006383 | Biological process | transcription by RNA polymerase III |
| GO_0097550 | Cellular component | transcription preinitiation complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0000126 | Cellular component | transcription factor TFIIIB complex |
| GO_0005634 | Cellular component | nucleus |
| GO_0017025 | Molecular function | TBP-class protein binding |
| GO_0000995 | Molecular function | RNA polymerase III general transcription initiation factor activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0001006 | Molecular function | RNA polymerase III type 3 promoter sequence-specific DNA binding |
| GO_0046872 | Molecular function | metal ion binding |
| Gene name | BRF1 |
| Protein name | BRF1 RNA polymerase III transcription initiation factor subunit (BRF1 protein) Transcription factor IIIB 90 kDa subunit (TFIIIB90) (hTFIIIB90) (B-related factor 1) (BRF-1) (hBRF) (TAF3B2) (TATA box-binding protein-associated factor, RNA polymerase III, subunit 2) BRF1 protein BRF1 RNA polymerase III transcription initiation factor subunit |
| Synonyms | GTF3B TAF3B2 BRF TAF3C |
| Description | FUNCTION: General activator of RNA polymerase which utilizes different TFIIIB complexes at structurally distinct promoters. The isoform 1 is involved in the transcription of tRNA, adenovirus VA1, 7SL and 5S RNA. Isoform 2 is required for transcription of the U6 promoter. |
| Accessions | ENST00000327359.7 [Q92994-7] ENST00000552127.5 ENST00000550208.1 Q92994 F8VS45 ENST00000619151.4 H0YIV6 ENST00000546417.5 F8VWT8 ENST00000548421.2 [Q92994-6] ENST00000547530.7 [Q92994-1] F8VXJ4 ENST00000392557.8 [Q92994-3] ENST00000549655.5 ENST00000379937.6 [Q92994-5] ENST00000446501.6 [Q92994-9] A3KN61 ENST00000550692.1 ENST00000551787.5 ENST00000440513.7 [Q92994-8] F8W123 Q3SYD8 F8VWY1 Q3SYD7 ENST00000550375.1 |
