BLOC1S5 | OmnibusX

Name	Number of supported studies	Average coverage
epithelial cell	3 studies	22% ± 5%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of BLOC1S5 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	606.27	1445 / 1445	100%	9.93	183 / 183
breast	100%	876.42	459 / 459	100%	17.18	1117 / 1118
prostate	100%	670.86	245 / 245	100%	12.92	501 / 502
lung	100%	549.99	577 / 578	100%	13.94	1154 / 1155
uterus	100%	758.02	170 / 170	100%	13.88	457 / 459
ovary	100%	701.81	180 / 180	100%	12.66	428 / 430
thymus	100%	731.96	653 / 653	100%	15.58	602 / 605
bladder	100%	816.95	21 / 21	99%	13.84	501 / 504
brain	99%	343.46	2628 / 2642	100%	11.90	703 / 705
liver	100%	546.32	226 / 226	99%	12.84	402 / 406
stomach	100%	513.60	359 / 359	99%	11.89	283 / 286
intestine	100%	686.56	966 / 966	99%	13.10	521 / 527
adrenal gland	100%	852.77	258 / 258	99%	10.24	227 / 230
kidney	100%	1326.98	89 / 89	99%	28.24	888 / 901
pancreas	99%	326.94	326 / 328	99%	10.98	176 / 178
skin	100%	816.03	1808 / 1809	98%	19.00	461 / 472
adipose	100%	872.13	1204 / 1204	0%	0	0 / 0
blood vessel	100%	797.50	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	21.40	29 / 29
spleen	100%	695.09	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	12.65	45 / 45
ureter	0%	0	0 / 0	100%	7.83	1 / 1
muscle	100%	476.08	799 / 803	0%	0	0 / 0
heart	99%	428.95	850 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	95%	11.96	76 / 80
peripheral blood	94%	595.73	873 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0008089	Biological process	anterograde axonal transport
GO_0035646	Biological process	endosome to melanosome transport
GO_0032402	Biological process	melanosome transport
GO_0048490	Biological process	anterograde synaptic vesicle transport
GO_0016192	Biological process	vesicle-mediated transport
GO_0032438	Biological process	melanosome organization
GO_0050942	Biological process	positive regulation of pigment cell differentiation
GO_0032474	Biological process	otolith morphogenesis
GO_0031175	Biological process	neuron projection development
GO_1990742	Cellular component	microvesicle
GO_0031083	Cellular component	BLOC-1 complex
GO_0030133	Cellular component	transport vesicle
GO_1904115	Cellular component	axon cytoplasm
GO_0005515	Molecular function	protein binding

Gene name	BLOC1S5
Protein name	Biogenesis of lysosome-related organelles complex 1 subunit 5 (Protein Muted homolog) Biogenesis of lysosome-related organelles complex 1 subunit 5 (BLOC-1 subunit 5) (Protein Muted homolog)
Synonyms	hCG_15560 MUTED
Description	FUNCTION: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes . In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking. .
Accessions	Q8TDH9 G5E931 ENST00000397457.7 [Q8TDH9-1] ENST00000627748.2 A0A0A0MTN6 A0A0D9SEU2 ENST00000244777.6 ENST00000543936.7

BLOC1S5 report