Insufficient scRNA-seq data for expression of BECN2 at single-cell level.
Insufficient scRNA-seq data for expression of BECN2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 37% | 1.30 | 169 / 459 | 2% | 0.03 | 20 / 1118 |
ovary | 30% | 0.93 | 54 / 180 | 5% | 0.08 | 21 / 430 |
lung | 20% | 0.50 | 117 / 578 | 3% | 0.07 | 40 / 1155 |
adipose | 21% | 0.66 | 258 / 1204 | 0% | 0 | 0 / 0 |
liver | 18% | 0.41 | 40 / 226 | 1% | 0.02 | 4 / 406 |
adrenal gland | 18% | 0.38 | 46 / 258 | 0% | 0 | 0 / 230 |
intestine | 15% | 0.37 | 146 / 966 | 2% | 0.04 | 8 / 527 |
esophagus | 10% | 0.24 | 150 / 1445 | 5% | 0.10 | 9 / 183 |
spleen | 14% | 0.30 | 33 / 241 | 0% | 0 | 0 / 0 |
skin | 12% | 0.30 | 216 / 1809 | 0% | 0.00 | 1 / 472 |
uterus | 8% | 0.18 | 13 / 170 | 2% | 0.04 | 9 / 459 |
stomach | 8% | 0.20 | 29 / 359 | 1% | 0.02 | 4 / 286 |
muscle | 9% | 0.19 | 69 / 803 | 0% | 0 | 0 / 0 |
pancreas | 6% | 0.12 | 21 / 328 | 1% | 0.01 | 2 / 178 |
kidney | 4% | 0.09 | 4 / 89 | 2% | 0.03 | 15 / 901 |
bladder | 5% | 0.19 | 1 / 21 | 1% | 0.02 | 6 / 504 |
blood vessel | 5% | 0.10 | 71 / 1335 | 0% | 0 | 0 / 0 |
brain | 5% | 0.11 | 129 / 2642 | 0% | 0.01 | 1 / 705 |
prostate | 4% | 0.05 | 9 / 245 | 0% | 0.01 | 2 / 502 |
thymus | 4% | 0.06 | 24 / 653 | 0% | 0 | 0 / 605 |
heart | 3% | 0.04 | 24 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 2% | 0.03 | 21 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_1990172 | Biological process | G protein-coupled receptor catabolic process |
GO_0045324 | Biological process | late endosome to vacuole transport |
GO_0000423 | Biological process | mitophagy |
GO_0006914 | Biological process | autophagy |
GO_0006995 | Biological process | cellular response to nitrogen starvation |
GO_0008333 | Biological process | endosome to lysosome transport |
GO_0000045 | Biological process | autophagosome assembly |
GO_0034271 | Cellular component | phosphatidylinositol 3-kinase complex, class III, type I |
GO_0034272 | Cellular component | phosphatidylinositol 3-kinase complex, class III, type II |
GO_0000407 | Cellular component | phagophore assembly site |
GO_0030674 | Molecular function | protein-macromolecule adaptor activity |
GO_0005515 | Molecular function | protein binding |
GO_0043548 | Molecular function | phosphatidylinositol 3-kinase binding |
Gene name | BECN2 |
Protein name | Beclin-2 (Beclin-1 autophagy-related pseudogene 1) (Beclin-1-like protein 1) |
Synonyms | BECN1P1 BECN1L1 |
Description | FUNCTION: Involved in 2 distinct lysosomal degradation pathways: acts as a regulator of autophagy and as a regulator of G-protein coupled receptors turnover. Regulates degradation in lysosomes of a variety of G-protein coupled receptors via its interaction with GPRASP1/GASP1. . |
Accessions | ENST00000419583.2 A8MW95 |