BAG2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1901800Biological processpositive regulation of proteasomal protein catabolic process
GO_0032436Biological processpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO_0006457Biological processprotein folding
GO_0050821Biological processprotein stabilization
GO_0010954Biological processpositive regulation of protein processing
GO_1904667Biological processnegative regulation of ubiquitin protein ligase activity
GO_0019538Biological processprotein metabolic process
GO_0032091Biological processnegative regulation of protein binding
GO_0031397Biological processnegative regulation of protein ubiquitination
GO_0005874Cellular componentmicrotubule
GO_0030425Cellular componentdendrite
GO_0101031Cellular componentprotein folding chaperone complex
GO_0005829Cellular componentcytosol
GO_0030424Cellular componentaxon
GO_1901588Cellular componentdendritic microtubule
GO_0000774Molecular functionadenyl-nucleotide exchange factor activity
GO_0031072Molecular functionheat shock protein binding
GO_0042802Molecular functionidentical protein binding
GO_0031625Molecular functionubiquitin protein ligase binding
GO_0051087Molecular functionprotein-folding chaperone binding
GO_0044325Molecular functiontransmembrane transporter binding
GO_0048156Molecular functiontau protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameBAG2
Protein nameBAG family molecular chaperone regulator 2 (BAG-2) (Bcl-2-associated athanogene 2)
Synonyms
DescriptionFUNCTION: Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release . .

AccessionsENST00000370693.5 [O95816-1]
O95816