B4GALNT2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of B4GALNT2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of B4GALNT2 at tissue level.

III. Associated gene sets

GO_0018279Biological processprotein N-linked glycosylation via asparagine
GO_0043403Biological processskeletal muscle tissue regeneration
GO_0006047Biological processUDP-N-acetylglucosamine metabolic process
GO_0017038Biological processprotein import
GO_0009312Biological processoligosaccharide biosynthetic process
GO_0030259Biological processlipid glycosylation
GO_0098528Biological processskeletal muscle fiber differentiation
GO_0019276Biological processUDP-N-acetylgalactosamine metabolic process
GO_0022408Biological processnegative regulation of cell-cell adhesion
GO_0000139Cellular componentGolgi membrane
GO_0016020Cellular componentmembrane
GO_0008376Molecular functionacetylgalactosaminyltransferase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameB4GALNT2
Protein nameBeta-1,4 N-acetylgalactosaminyltransferase 2 (EC 2.4.1.-) (Sd(a) beta-1,4-GalNAc transferase) (UDP-GalNAc:Neu5Aca2-3Galb-R b1,4-N-acetylgalactosaminyltransferase)
SynonymsGALGT2
DescriptionFUNCTION: Involved in the synthesis of the Sd(a) antigen (Sia-alpha2,3-[GalNAc-beta1,4]Gal-beta1,4-GlcNAc), a carbohydrate determinant expressed on erythrocytes, the colonic mucosa and other tissues. Transfers a beta-1,4-linked GalNAc to the galactose residue of an alpha-2,3-sialylated chain. .

AccessionsENST00000300404.2 [Q8NHY0-1]
Q8NHY0
ENST00000393354.7 [Q8NHY0-2]
ENST00000504681.5 [Q8NHY0-3]