B3GALT6 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of B3GALT6 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of B3GALT6 at tissue level.

III. Associated gene sets

GO_0030203Biological processglycosaminoglycan metabolic process
GO_0015012Biological processheparan sulfate proteoglycan biosynthetic process
GO_0030166Biological processproteoglycan biosynthetic process
GO_0030206Biological processchondroitin sulfate biosynthetic process
GO_0006024Biological processglycosaminoglycan biosynthetic process
GO_0006493Biological processprotein O-linked glycosylation
GO_0000139Cellular componentGolgi membrane
GO_0032580Cellular componentGolgi cisterna membrane
GO_0005794Cellular componentGolgi apparatus
GO_0016020Cellular componentmembrane
GO_0005797Cellular componentGolgi medial cisterna
GO_0047220Molecular functiongalactosylxylosylprotein 3-beta-galactosyltransferase activity
GO_0035250Molecular functionUDP-galactosyltransferase activity

IV. Literature review

[source]
Gene nameB3GALT6
Protein nameBeta-1,3-galactosyltransferase 6 (Beta-1,3-GalTase 6) (Beta3Gal-T6) (Beta3GalT6) (EC 2.4.1.134) (GAG GalTII) (Galactosyltransferase II) (Galactosylxylosylprotein 3-beta-galactosyltransferase) (UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6)
Hexosyltransferase (EC 2.4.1.-)
Synonyms
DescriptionFUNCTION: Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-linked galactose residue. Has a preference for galactose-beta-1,4-xylose that is found in the linker region of glycosaminoglycans, such as heparan sulfate and chondroitin sulfate. Has no activity towards substrates with terminal glucosamine or galactosamine residues. .

AccessionsQ499Z2
Q96L58
ENST00000379198.5