ATRIP report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ATRIP at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ATRIP at tissue level.

III. Associated gene sets

GO_0006139Biological processnucleobase-containing compound metabolic process
GO_0006281Biological processDNA repair
GO_2000779Biological processregulation of double-strand break repair
GO_0000077Biological processDNA damage checkpoint signaling
GO_0070310Cellular componentATR-ATRIP complex
GO_0005654Cellular componentnucleoplasm
GO_0005634Cellular componentnucleus
GO_0070530Molecular functionK63-linked polyubiquitin modification-dependent protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameATRIP
Protein nameATR interacting protein
ATR interacting protein (Three prime repair exonuclease 1, isoform CRA_a)
ATR-interacting protein (ATM and Rad3-related-interacting protein)
SynonymsTREX1
hCG_1997849
AGS1
DescriptionFUNCTION: Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein. .

AccessionsENST00000320211.10 [Q8WXE1-1]
ENST00000412052.4 [Q8WXE1-3]
ENST00000346691.9 [Q8WXE1-2]
A0A0U1RQR9
A0A1W2PQ89
ENST00000639561.1
ENST00000634384.2
A0A0U1RQJ8
A0A0U1RQW3
A0A0U1RRM7
ENST00000635464.1
ENST00000635082.1
Q8WXE1
ENST00000635099.1