ATP6V1E2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ATP6V1E2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ATP6V1E2 at tissue level.

III. Associated gene sets

GO_0016241Biological processregulation of macroautophagy
GO_1902600Biological processproton transmembrane transport
GO_0033178Cellular componentproton-transporting two-sector ATPase complex, catalytic domain
GO_0001669Cellular componentacrosomal vesicle
GO_0005829Cellular componentcytosol
GO_0046961Molecular functionproton-transporting ATPase activity, rotational mechanism
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameATP6V1E2
Protein nameV-type proton ATPase subunit E 2 (V-ATPase subunit E 2) (Vacuolar proton pump subunit E 2)
ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2 (Testis secretory sperm-binding protein Li 235P)
SynonymsATP6V1EL2
ATP6EL2
hCG_1644366
ATP6E1
DescriptionFUNCTION: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. .

AccessionsQ96A05
ENST00000306448.4
A0A140VKA8
ENST00000522587.6