I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| goblet cell | 5 studies | 45% ± 13% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| goblet cell | 5 studies | 45% ± 13% |
Insufficient scRNA-seq data for expression of ATOH1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| intestine | 58% | 986.55 | 562 / 966 | 68% | 24.45 | 356 / 527 |
| stomach | 0% | 0 | 0 / 359 | 50% | 12.73 | 144 / 286 |
| prostate | 2% | 1.15 | 4 / 245 | 21% | 2.93 | 105 / 502 |
| esophagus | 0% | 0.30 | 3 / 1445 | 20% | 2.86 | 37 / 183 |
| bladder | 0% | 0 | 0 / 21 | 20% | 7.47 | 102 / 504 |
| pancreas | 0% | 0 | 0 / 328 | 13% | 4.09 | 23 / 178 |
| lung | 0% | 0 | 0 / 578 | 5% | 0.57 | 60 / 1155 |
| tonsil | 0% | 0 | 0 / 0 | 4% | 0.16 | 2 / 45 |
| uterus | 0% | 0 | 0 / 170 | 2% | 0.16 | 8 / 459 |
| ovary | 0% | 0 | 0 / 180 | 1% | 0.02 | 4 / 430 |
| liver | 0% | 0 | 0 / 226 | 1% | 0.09 | 3 / 406 |
| heart | 0% | 0.27 | 2 / 861 | 0% | 0 | 0 / 0 |
| breast | 0% | 2.04 | 1 / 459 | 0% | 0 | 0 / 1118 |
| brain | 0% | 0.05 | 1 / 2642 | 0% | 0.02 | 1 / 705 |
| thymus | 0% | 0 | 0 / 653 | 0% | 0.01 | 1 / 605 |
| kidney | 0% | 0 | 0 / 89 | 0% | 0.00 | 1 / 901 |
| adipose | 0% | 0.04 | 1 / 1204 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| adrenal gland | 0% | 0 | 0 / 258 | 0% | 0 | 0 / 230 |
| blood vessel | 0% | 0 | 0 / 1335 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| skin | 0% | 0 | 0 / 1809 | 0% | 0 | 0 / 472 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0045609 | Biological process | positive regulation of inner ear auditory receptor cell differentiation |
| GO_0042668 | Biological process | auditory receptor cell fate determination |
| GO_0006366 | Biological process | transcription by RNA polymerase II |
| GO_0061564 | Biological process | axon development |
| GO_0007219 | Biological process | Notch signaling pathway |
| GO_0048663 | Biological process | neuron fate commitment |
| GO_0014014 | Biological process | negative regulation of gliogenesis |
| GO_0001764 | Biological process | neuron migration |
| GO_1904036 | Biological process | negative regulation of epithelial cell apoptotic process |
| GO_1904019 | Biological process | epithelial cell apoptotic process |
| GO_0007417 | Biological process | central nervous system development |
| GO_0042472 | Biological process | inner ear morphogenesis |
| GO_0021987 | Biological process | cerebral cortex development |
| GO_0045666 | Biological process | positive regulation of neuron differentiation |
| GO_0097402 | Biological process | neuroblast migration |
| GO_0007423 | Biological process | sensory organ development |
| GO_0007411 | Biological process | axon guidance |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0042667 | Biological process | auditory receptor cell fate specification |
| GO_0000785 | Cellular component | chromatin |
| GO_0005634 | Cellular component | nucleus |
| GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
| GO_0003700 | Molecular function | DNA-binding transcription factor activity |
| GO_0031490 | Molecular function | chromatin DNA binding |
| GO_0070888 | Molecular function | E-box binding |
| GO_0046983 | Molecular function | protein dimerization activity |
| Gene name | ATOH1 |
| Protein name | Transcription factor ATOH1 (Atonal bHLH transcription factor 1) (Class A basic helix-loop-helix protein 14) (bHLHa14) (Helix-loop-helix protein hATH-1) (hATH1) (Protein atonal homolog 1) ATOH1 protein |
| Synonyms | ATH1 BHLHA14 |
| Description | FUNCTION: Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity). . |
| Accessions | Q6ISE7 Q92858 ENST00000306011.6 |
