Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 6 studies | 21% ± 4% | |
natural killer cell | 5 studies | 25% ± 9% | |
plasmablast | 4 studies | 30% ± 14% | |
CD4-positive, alpha-beta T cell | 4 studies | 22% ± 6% | |
epithelial cell | 4 studies | 21% ± 6% | |
pro-B cell | 4 studies | 24% ± 5% | |
dendritic cell | 4 studies | 17% ± 2% | |
CD8-positive, alpha-beta T cell | 4 studies | 25% ± 5% | |
B cell | 3 studies | 18% ± 2% | |
hematopoietic precursor cell | 3 studies | 25% ± 7% | |
abnormal cell | 3 studies | 28% ± 17% | |
lymphocyte | 3 studies | 20% ± 4% | |
GABAergic neuron | 3 studies | 37% ± 5% | |
glutamatergic neuron | 3 studies | 48% ± 2% | |
neural progenitor cell | 3 studies | 21% ± 2% | |
megakaryocyte-erythroid progenitor cell | 3 studies | 22% ± 1% | |
transit amplifying cell | 3 studies | 49% ± 27% | |
astrocyte | 3 studies | 31% ± 8% | |
cardiac muscle cell | 3 studies | 23% ± 4% | |
effector CD8-positive, alpha-beta T cell | 3 studies | 22% ± 2% | |
T cell | 3 studies | 20% ± 2% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 4 studies | 29% ± 12% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 1103.21 | 1443 / 1445 | 100% | 49.12 | 183 / 183 |
breast | 100% | 971.13 | 458 / 459 | 98% | 48.07 | 1101 / 1118 |
uterus | 100% | 836.31 | 170 / 170 | 98% | 47.13 | 448 / 459 |
stomach | 100% | 1026.16 | 359 / 359 | 97% | 30.13 | 278 / 286 |
ovary | 100% | 1629.93 | 180 / 180 | 97% | 24.66 | 415 / 430 |
bladder | 100% | 886.19 | 21 / 21 | 96% | 28.39 | 485 / 504 |
lung | 100% | 1210.15 | 576 / 578 | 97% | 29.57 | 1115 / 1155 |
intestine | 99% | 802.67 | 960 / 966 | 96% | 26.92 | 506 / 527 |
prostate | 100% | 1544.37 | 245 / 245 | 95% | 18.45 | 475 / 502 |
skin | 100% | 2090.92 | 1805 / 1809 | 92% | 24.81 | 432 / 472 |
brain | 99% | 669.76 | 2608 / 2642 | 92% | 15.18 | 647 / 705 |
thymus | 99% | 731.70 | 649 / 653 | 88% | 13.93 | 532 / 605 |
liver | 100% | 800.52 | 226 / 226 | 83% | 19.97 | 335 / 406 |
pancreas | 87% | 362.91 | 285 / 328 | 82% | 12.35 | 146 / 178 |
adrenal gland | 100% | 837.59 | 258 / 258 | 53% | 7.57 | 123 / 230 |
blood vessel | 100% | 1596.97 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 31.35 | 29 / 29 |
spleen | 100% | 989.54 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 54.70 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 11.99 | 1 / 1 |
adipose | 100% | 789.29 | 1201 / 1204 | 0% | 0 | 0 / 0 |
heart | 93% | 852.43 | 802 / 861 | 0% | 0 | 0 / 0 |
kidney | 43% | 210.53 | 38 / 89 | 36% | 3.78 | 324 / 901 |
muscle | 76% | 1504.25 | 609 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 60% | 1966.85 | 558 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 24% | 3.06 | 19 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006337 | Biological process | nucleosome disassembly |
GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
GO_0045815 | Biological process | transcription initiation-coupled chromatin remodeling |
GO_0006334 | Biological process | nucleosome assembly |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0005515 | Molecular function | protein binding |
GO_0016887 | Molecular function | ATP hydrolysis activity |
GO_0042393 | Molecular function | histone binding |
GO_0003682 | Molecular function | chromatin binding |
GO_0005524 | Molecular function | ATP binding |
Gene name | ATAD2 |
Protein name | ATPase family AAA domain containing 2 ATPase family AAA domain-containing protein 2 (EC 3.6.1.-) (AAA nuclear coregulator cancer-associated protein) (ANCCA) |
Synonyms | L16 PRO2000 |
Description | FUNCTION: May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells. . |
Accessions | E5RIP2 A0A0B4J211 ENST00000517666.5 ENST00000519124.5 Q6PL18 ENST00000521903.5 E5RHW7 ENST00000287394.10 [Q6PL18-1] |