ATAD2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006337Biological processnucleosome disassembly
GO_0045893Biological processpositive regulation of DNA-templated transcription
GO_0045815Biological processtranscription initiation-coupled chromatin remodeling
GO_0006334Biological processnucleosome assembly
GO_0070062Cellular componentextracellular exosome
GO_0005654Cellular componentnucleoplasm
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding
GO_0016887Molecular functionATP hydrolysis activity
GO_0042393Molecular functionhistone binding
GO_0003682Molecular functionchromatin binding
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameATAD2
Protein nameATPase family AAA domain containing 2
ATPase family AAA domain-containing protein 2 (EC 3.6.1.-) (AAA nuclear coregulator cancer-associated protein) (ANCCA)
SynonymsL16
PRO2000
DescriptionFUNCTION: May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells. .

AccessionsE5RIP2
A0A0B4J211
ENST00000517666.5
ENST00000519124.5
Q6PL18
ENST00000521903.5
E5RHW7
ENST00000287394.10 [Q6PL18-1]