ASPG report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ASPG at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ASPG at tissue level.

III. Associated gene sets

GO_0009066Biological processaspartate family amino acid metabolic process
GO_0016042Biological processlipid catabolic process
GO_0005829Cellular componentcytosol
GO_0004067Molecular functionasparaginase activity
GO_0004622Molecular functionlysophospholipase activity
GO_0003847Molecular function1-alkyl-2-acetylglycerophosphocholine esterase activity
GO_0016747Molecular functionacyltransferase activity, transferring groups other than amino-acyl groups
GO_0102545Molecular functionphosphatidyl phospholipase B activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameASPG
Protein nameasparaginase (EC 3.5.1.1)
Asparaginase
60 kDa lysophospholipase (LysoLP) (EC 3.1.1.5) (Lysophospholipase-transacylase) [Includes: L-asparaginase (EC 3.5.1.1) (L-asparagine amidohydrolase); 1-alkyl-2-acetylglycerophosphocholine esterase (EC 3.1.1.47) (Platelet-activating factor acetylhydrolase) (PAF acetylhydrolase)]
SynonymsC14orf76
hCG_23215
DescriptionFUNCTION: Exhibits lysophospholipase, transacylase, PAF acetylhydrolase and asparaginase activities (By similarity). Can catalyze three types of transacylation reactions: (1) acyl transfer from 1-acyl-sn-glycero-3-phosphocholine (1-acyl-GPC) to the sn-1(3) positions of glycerol and 2-acylglycerol (sn-1 to -1(3) transfer), (2) acyl transfer from 1-acyl-GPC to the sn-2 positions of 1-acyl-GPC, 1-acyl-sn-glycero-3-phosphoethanolamine (1-acyl-GPE), and other lysophospholipids (sn-1 to -2 transfer) and (3) acyl transfer from 2-acyl-GPC to the sn-1 position of 2-acyl-GPC and 2-acyl-GPE (sn-2 to -1 transfer) (By similarity). Mediates the synthesis of 1-arachidonoyl species of phospholipids by transferring the arachidonoyl residue from 2-arachidonoyl lysophospholipid to the sn-1 position of 2-acyl lysophospholipid (By similarity). .

AccessionsH0YHD3
G3V1Y8
ENST00000551170.1
ENST00000550583.1
Q86U10
ENST00000551177.6 [Q86U10-1]
ENST00000546892.6
H0YHG5