ASIC3 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of ASIC3 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	1838.68	2633 / 2642	100%	15.02	703 / 705
prostate	99%	628.25	242 / 245	83%	2.90	419 / 502
ovary	100%	685.48	180 / 180	73%	2.84	316 / 430
uterus	100%	1172.30	170 / 170	72%	2.76	332 / 459
breast	84%	304.12	387 / 459	74%	2.89	831 / 1118
lung	96%	377.26	553 / 578	58%	2.04	671 / 1155
adrenal gland	62%	176.57	159 / 258	91%	7.44	210 / 230
kidney	94%	377.65	84 / 89	53%	1.53	478 / 901
skin	65%	218.46	1177 / 1809	80%	3.09	378 / 472
esophagus	84%	432.56	1211 / 1445	60%	1.79	110 / 183
thymus	98%	477.66	642 / 653	42%	1.10	254 / 605
intestine	96%	617.15	929 / 966	41%	1.13	218 / 527
bladder	90%	356.71	19 / 21	46%	1.46	234 / 504
liver	63%	180.18	142 / 226	59%	1.70	238 / 406
stomach	73%	313.23	263 / 359	41%	0.83	118 / 286
pancreas	23%	51.63	74 / 328	82%	2.50	146 / 178
ureter	0%	0	0 / 0	100%	1.17	1 / 1
heart	95%	563.42	821 / 861	0%	0	0 / 0
spleen	95%	311.82	229 / 241	0%	0	0 / 0
muscle	93%	413.20	748 / 803	0%	0	0 / 0
adipose	79%	251.47	956 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	76%	2.07	61 / 80
lymph node	0%	0	0 / 0	76%	2.04	22 / 29
blood vessel	58%	155.21	775 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	53%	1.58	24 / 45
peripheral blood	26%	57.63	238 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0007165	Biological process	signal transduction
GO_0042930	Biological process	enterobactin transport
GO_0050966	Biological process	detection of mechanical stimulus involved in sensory perception of pain
GO_0009408	Biological process	response to heat
GO_0007600	Biological process	sensory perception
GO_0035725	Biological process	sodium ion transmembrane transport
GO_0050965	Biological process	detection of temperature stimulus involved in sensory perception of pain
GO_0051649	Biological process	establishment of localization in cell
GO_0050915	Biological process	sensory perception of sour taste
GO_0010447	Biological process	response to acidic pH
GO_0050968	Biological process	detection of chemical stimulus involved in sensory perception of pain
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0005886	Cellular component	plasma membrane
GO_0160128	Molecular function	pH-gated monoatomic ion channel activity
GO_0005272	Molecular function	sodium channel activity
GO_0042931	Molecular function	enterobactin transmembrane transporter activity
GO_0015280	Molecular function	ligand-gated sodium channel activity
GO_0005261	Molecular function	monoatomic cation channel activity

Gene name	ASIC3
Protein name	Acid-sensing ion channel 3 (ASIC3) (hASIC3) (Amiloride-sensitive cation channel 3) (Neuronal amiloride-sensitive cation channel 3) (Testis sodium channel 1) (hTNaC1) Acid sensing ion channel subunit 3
Synonyms	SLNAC1 TNAC1 ACCN3
Description	FUNCTION: Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Generates a biphasic current with a fast inactivating and a slow sustained phase. In sensory neurons is proposed to mediate the pain induced by acidosis that occurs in ischemic, damaged or inflamed tissue. May be involved in hyperalgesia. May play a role in mechanoreception. Heteromeric channel assembly seems to modulate channel properties. .
Accessions	ENST00000490540.1 ENST00000349064.10 [Q9UHC3-1] ENST00000377904.8 [Q9UHC3-4] Q9UHC3 ENST00000485929.5 ENST00000357922.8 [Q9UHC3-2] ENST00000297512.12 [Q9UHC3-3] H7C4W0 ENST00000468325.5 [Q9UHC3-4] H7C5N6

ASIC3 report