Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| astrocyte | 14 studies | 42% ± 24% | |
| type I pneumocyte | 11 studies | 53% ± 18% | |
| fibroblast | 8 studies | 20% ± 4% | |
| endothelial cell | 5 studies | 24% ± 7% | |
| Mueller cell | 5 studies | 34% ± 12% | |
| adipocyte | 4 studies | 19% ± 2% | |
| GABAergic neuron | 3 studies | 24% ± 6% | |
| glial cell | 3 studies | 32% ± 8% | |
| hepatocyte | 3 studies | 71% ± 24% | |
| Schwann cell | 3 studies | 47% ± 21% | |
| oligodendrocyte precursor cell | 3 studies | 28% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 1883.28 | 244 / 245 | 100% | 66.96 | 501 / 502 |
| brain | 90% | 1673.78 | 2374 / 2642 | 99% | 52.73 | 699 / 705 |
| breast | 97% | 1734.02 | 447 / 459 | 88% | 17.77 | 979 / 1118 |
| thymus | 97% | 1294.03 | 632 / 653 | 80% | 9.46 | 482 / 605 |
| liver | 100% | 2750.01 | 225 / 226 | 76% | 11.22 | 310 / 406 |
| lung | 100% | 4173.56 | 578 / 578 | 67% | 12.48 | 775 / 1155 |
| uterus | 99% | 1668.21 | 169 / 170 | 56% | 7.19 | 256 / 459 |
| esophagus | 100% | 5049.91 | 1440 / 1445 | 54% | 9.07 | 99 / 183 |
| skin | 81% | 1806.93 | 1463 / 1809 | 56% | 8.62 | 264 / 472 |
| bladder | 100% | 2086.62 | 21 / 21 | 31% | 3.90 | 155 / 504 |
| stomach | 90% | 2802.51 | 324 / 359 | 23% | 2.87 | 67 / 286 |
| intestine | 92% | 4878.08 | 892 / 966 | 19% | 1.51 | 100 / 527 |
| ovary | 97% | 1250.44 | 174 / 180 | 12% | 0.91 | 50 / 430 |
| pancreas | 67% | 696.91 | 221 / 328 | 35% | 4.10 | 62 / 178 |
| blood vessel | 99% | 2898.68 | 1325 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 91% | 1433.64 | 1092 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 76% | 10.95 | 34 / 45 |
| kidney | 54% | 524.67 | 48 / 89 | 5% | 0.40 | 47 / 901 |
| adrenal gland | 22% | 176.67 | 56 / 258 | 30% | 2.73 | 70 / 230 |
| heart | 42% | 443.02 | 359 / 861 | 0% | 0 | 0 / 0 |
| spleen | 12% | 118.51 | 30 / 241 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 10% | 0.97 | 3 / 29 |
| eye | 0% | 0 | 0 / 0 | 3% | 0.21 | 2 / 80 |
| muscle | 0% | 2.81 | 3 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0001886 | Biological process | endothelial cell morphogenesis |
| GO_0097178 | Biological process | ruffle assembly |
| GO_0090630 | Biological process | activation of GTPase activity |
| GO_0001726 | Cellular component | ruffle |
| GO_0005829 | Cellular component | cytosol |
| GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
| Gene name | ARHGEF26 |
| Protein name | Rho guanine nucleotide exchange factor 26 (SH3 domain-containing guanine exchange factor) ARHGEF26 |
| Synonyms | SGEF HMFN1864 |
| Description | FUNCTION: Activates RhoG GTPase by promoting the exchange of GDP by GTP. Required for the formation of membrane ruffles during macropinocytosis. Required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry. . |
| Accessions | ENST00000356448.8 [Q96DR7-1] ENST00000496710.5 [Q96DR7-4] ENST00000465093.6 [Q96DR7-1] ENST00000618535.3 [Q96DR7-1] ENST00000465817.1 [Q96DR7-3] A0A2X0U4M4 ENST00000614308.3 [Q96DR7-1] ENST00000630729.2 [Q96DR7-4] Q96DR7 ENST00000629129.2 [Q96DR7-3] |
