ARHGDIG report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007266Biological processRho protein signal transduction
GO_0032880Biological processregulation of protein localization
GO_0007162Biological processnegative regulation of cell adhesion
GO_0001835Biological processblastocyst hatching
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0031410Cellular componentcytoplasmic vesicle
GO_0016020Cellular componentmembrane
GO_0005094Molecular functionRho GDP-dissociation inhibitor activity
GO_0005515Molecular functionprotein binding
GO_0005096Molecular functionGTPase activator activity

IV. Literature review

[source]
Gene nameARHGDIG
Protein nameRho GDP dissociation inhibitor (GDI) gamma
Rho GDP-dissociation inhibitor 3 (Rho GDI 3) (Rho-GDI gamma)
HCG1985507, isoform CRA_a (Rho GDP-dissociation inhibitor 3)
Rho GDP dissociation inhibitor gamma
Rho GDP dissociation inhibitor (GDI) gamma (Rho GDP dissociation inhibitor gamma)
SynonymsLA16c-314G4.1-002
LA16c-314G4.1-004
LA16c-314G4.1-005
LA16c-314G4.1-006
hCG_1985507
DescriptionFUNCTION: Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post-translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP.

AccessionsA2ID99
A2IDA1
ENST00000447871.5
C9J3B5
Q4TT68
Q99819
F1T0H7
A2IDA0
ENST00000414650.1
ENST00000219409.8