Name | Number of supported studies | Average coverage | |
---|---|---|---|
pericyte | 18 studies | 36% ± 18% | |
fibroblast | 11 studies | 44% ± 11% | |
smooth muscle cell | 11 studies | 35% ± 14% | |
macrophage | 10 studies | 39% ± 17% | |
microglial cell | 10 studies | 41% ± 14% | |
mast cell | 10 studies | 26% ± 8% | |
endothelial cell | 9 studies | 29% ± 10% | |
platelet | 8 studies | 30% ± 10% | |
oligodendrocyte precursor cell | 5 studies | 29% ± 9% | |
myofibroblast cell | 4 studies | 37% ± 11% | |
mesothelial cell | 4 studies | 51% ± 23% | |
myeloid cell | 4 studies | 32% ± 6% | |
luminal cell of prostate epithelium | 4 studies | 31% ± 19% | |
capillary endothelial cell | 4 studies | 27% ± 9% | |
dendritic cell | 3 studies | 24% ± 3% | |
GABAergic neuron | 3 studies | 41% ± 9% | |
glutamatergic neuron | 3 studies | 35% ± 8% | |
megakaryocyte | 3 studies | 72% ± 10% | |
alveolar macrophage | 3 studies | 21% ± 3% | |
ciliated cell | 3 studies | 33% ± 12% | |
muscle cell | 3 studies | 36% ± 21% | |
interneuron | 3 studies | 41% ± 19% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 4439.93 | 245 / 245 | 100% | 39.76 | 502 / 502 |
kidney | 100% | 982.67 | 89 / 89 | 93% | 8.33 | 841 / 901 |
thymus | 100% | 4041.49 | 652 / 653 | 87% | 11.60 | 529 / 605 |
stomach | 82% | 835.82 | 296 / 359 | 50% | 3.43 | 143 / 286 |
intestine | 96% | 2331.13 | 931 / 966 | 35% | 1.93 | 182 / 527 |
bladder | 100% | 2644.76 | 21 / 21 | 29% | 2.11 | 145 / 504 |
breast | 100% | 1586.74 | 457 / 459 | 25% | 1.03 | 277 / 1118 |
lung | 100% | 2840.02 | 577 / 578 | 23% | 1.10 | 262 / 1155 |
brain | 44% | 363.67 | 1166 / 2642 | 78% | 4.48 | 547 / 705 |
uterus | 100% | 3154.35 | 170 / 170 | 21% | 1.72 | 96 / 459 |
ovary | 100% | 2930.30 | 180 / 180 | 16% | 0.67 | 69 / 430 |
esophagus | 83% | 1327.41 | 1200 / 1445 | 32% | 1.65 | 59 / 183 |
adipose | 100% | 2461.82 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1794.38 | 1334 / 1335 | 0% | 0 | 0 / 0 |
spleen | 99% | 1271.67 | 239 / 241 | 0% | 0 | 0 / 0 |
muscle | 99% | 1324.00 | 792 / 803 | 0% | 0 | 0 / 0 |
skin | 70% | 536.84 | 1260 / 1809 | 21% | 2.08 | 101 / 472 |
heart | 87% | 553.81 | 746 / 861 | 0% | 0 | 0 / 0 |
pancreas | 13% | 52.30 | 41 / 328 | 65% | 3.00 | 116 / 178 |
adrenal gland | 9% | 38.21 | 24 / 258 | 17% | 0.76 | 40 / 230 |
peripheral blood | 15% | 161.24 | 135 / 929 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 9% | 0.24 | 4 / 45 |
liver | 1% | 5.88 | 3 / 226 | 4% | 0.14 | 18 / 406 |
eye | 0% | 0 | 0 / 0 | 1% | 0.10 | 1 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007266 | Biological process | Rho protein signal transduction |
GO_0051056 | Biological process | regulation of small GTPase mediated signal transduction |
GO_0030041 | Biological process | actin filament polymerization |
GO_0051895 | Biological process | negative regulation of focal adhesion assembly |
GO_0051497 | Biological process | negative regulation of stress fiber assembly |
GO_0048041 | Biological process | focal adhesion assembly |
GO_0015629 | Cellular component | actin cytoskeleton |
GO_0005737 | Cellular component | cytoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0005884 | Cellular component | actin filament |
GO_0016004 | Molecular function | phospholipase activator activity |
GO_0043274 | Molecular function | phospholipase binding |
GO_0005096 | Molecular function | GTPase activator activity |
GO_0017124 | Molecular function | SH3 domain binding |
Gene name | ARHGAP6 |
Protein name | Rho GTPase-activating protein 6 (Rho-type GTPase-activating protein 6) (Rho-type GTPase-activating protein RhoGAPX-1) Rho GTPase activating protein 6 Rho GTPase activating protein 6 (cDNA FLJ59725, highly similar to Rho-GTPase-activating protein 6) |
Synonyms | RHOGAP6 |
Description | FUNCTION: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Could regulate the interactions of signaling molecules with the actin cytoskeleton. Promotes continuous elongation of cytoplasmic processes during cell motility and simultaneous retraction of the cell body changing the cell morphology. . |
Accessions | ENST00000337414.9 [O43182-1] O43182 ENST00000380718.1 [O43182-2] ENST00000380736.5 [O43182-4] ENST00000303025.10 [O43182-4] ENST00000495242.5 [O43182-3] H7BYE6 ENST00000380717.7 B4DN07 ENST00000657361.1 |