ARHGAP1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007266Biological processRho protein signal transduction
GO_0051056Biological processregulation of small GTPase mediated signal transduction
GO_2001136Biological processnegative regulation of endocytic recycling
GO_0016197Biological processendosomal transport
GO_0007264Biological processsmall GTPase-mediated signal transduction
GO_0033572Biological processtransferrin transport
GO_0097443Cellular componentsorting endosome
GO_0010008Cellular componentendosome membrane
GO_0070062Cellular componentextracellular exosome
GO_0005829Cellular componentcytosol
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0005737Cellular componentcytoplasm
GO_0045296Molecular functioncadherin binding
GO_0005515Molecular functionprotein binding
GO_0031267Molecular functionsmall GTPase binding
GO_0005096Molecular functionGTPase activator activity
GO_0017124Molecular functionSH3 domain binding

IV. Literature review

[source]
Gene nameARHGAP1
Protein nameRho GTPase activating protein 1
Rho GTPase-activating protein 1 (CDC42 GTPase-activating protein) (GTPase-activating protein rhoGAP) (Rho-related small GTPase protein activator) (Rho-type GTPase-activating protein 1) (p50-RhoGAP)
SynonymsCDC42GAP
RHOGAP1
DescriptionFUNCTION: GTPase activator for the Rho, Rac and Cdc42 proteins, converting them to the putatively inactive GDP-bound state. Cdc42 seems to be the preferred substrate.

AccessionsH0YE29
ENST00000311956.9
E9PNR6
ENST00000525488.1
ENST00000528837.5
Q07960