AQP7 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006833Biological processwater transport
GO_0071918Biological processurea transmembrane transport
GO_0015793Biological processglycerol transmembrane transport
GO_0005911Cellular componentcell-cell junction
GO_0005938Cellular componentcell cortex
GO_0005886Cellular componentplasma membrane
GO_0030659Cellular componentcytoplasmic vesicle membrane
GO_0005811Cellular componentlipid droplet
GO_0016323Cellular componentbasolateral plasma membrane
GO_0005737Cellular componentcytoplasm
GO_0015250Molecular functionwater channel activity
GO_0015254Molecular functionglycerol channel activity
GO_0005515Molecular functionprotein binding
GO_0015204Molecular functionurea transmembrane transporter activity

IV. Literature review

[source]
Gene nameAQP7
Protein nameAquaporin 7
AQP7 protein (Aquaporin 7)
Aquaporin 7 (cDNA FLJ52444, highly similar to Aquaporin-7)
Aquaporin 7 (cDNA FLJ60727, highly similar to Aquaporin-7)
Aquaporin-7 (AQP-7) (Aquaglyceroporin-7) (Aquaporin adipose) (AQPap) (Aquaporin-7-like)
SynonymsAQP7L
hCG_2011318
AQP9
DescriptionFUNCTION: Forms a channel that mediates water and glycerol transport across cell membranes at neutral pH . The channel is also permeable to urea . Plays an important role in body energy homeostasis under conditions that promote lipid catabolism, giving rise to glycerol and free fatty acids. Mediates glycerol export from adipocytes. After release into the blood stream, glycerol is used for gluconeogenesis in the liver to maintain normal blood glucose levels and prevent fasting hypoglycemia. Required for normal glycerol reabsorption in the kidney (By similarity). .

AccessionsB7Z4U2
A0A096LNU3
ENST00000624420.3
A0A096LNN5
Q6P5T0
A0A096LP64
ENST00000624005.3
Q5T5M1
ENST00000447660.3 [O14520-2]
ENST00000624890.3
Q5T5M0
A0A096LNK2
ENST00000297988.6 [O14520-1]
ENST00000379507.7
ENST00000537089.5
ENST00000379506.7
ENST00000439678.5
ENST00000624095.1
ENST00000624075.3
A0A096LP23
ENST00000377425.8
O14520
ENST00000625032.1
ENST00000625109.3
Q5T5L3
A0A096LNV7