APOOL report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007007Biological processinner mitochondrial membrane organization
GO_0042407Biological processcristae formation
GO_0001401Cellular componentSAM complex
GO_0031093Cellular componentplatelet alpha granule lumen
GO_0005576Cellular componentextracellular region
GO_0044284Cellular componentmitochondrial crista junction
GO_0061617Cellular componentMICOS complex
GO_0005743Cellular componentmitochondrial inner membrane
GO_0005739Cellular componentmitochondrion
GO_0140275Cellular componentMIB complex
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameAPOOL
Protein nameMICOS complex subunit MIC27 (Apolipoprotein O-like) (Protein FAM121A)
SynonymsMIC27
FAM121A
UNQ8193/PRO23204
CXorf33
DescriptionFUNCTION: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol. Plays a crucial role in crista junction formation and mitochondrial function , . .

AccessionsENST00000373173.7
Q6UXV4