APOBEC2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of APOBEC2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of APOBEC2 at tissue level.

III. Associated gene sets

GO_0016554Biological processcytidine to uridine editing
GO_0006397Biological processmRNA processing
GO_0009972Biological processcytidine deamination
GO_0044029Biological processpositive regulation of gene expression via chromosomal CpG island demethylation
GO_0016556Biological processmRNA modification
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0042802Molecular functionidentical protein binding
GO_0046872Molecular functionmetal ion binding
GO_0004126Molecular functioncytidine deaminase activity
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameAPOBEC2
Protein nameC->U-editing enzyme APOBEC-2 (EC 3.5.4.36) (mRNA(cytosine(6666)) deaminase 2)
Synonyms
DescriptionFUNCTION: Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation. .

AccessionsQ9Y235
ENST00000244669.3