APBA3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of APBA3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of APBA3 at tissue level.

III. Associated gene sets

GO_0015031Biological processprotein transport
GO_0010468Biological processregulation of gene expression
GO_0007268Biological processchemical synaptic transmission
GO_0001701Biological processin utero embryonic development
GO_0043086Biological processnegative regulation of catalytic activity
GO_0005886Cellular componentplasma membrane
GO_0043197Cellular componentdendritic spine
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0005737Cellular componentcytoplasm
GO_0019899Molecular functionenzyme binding
GO_0001540Molecular functionamyloid-beta binding
GO_0004857Molecular functionenzyme inhibitor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameAPBA3
Protein nameAmyloid-beta A4 precursor protein-binding family A member 3 (Adapter protein X11gamma) (Neuron-specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3)
SynonymsMINT3
X11L2
DescriptionFUNCTION: May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta. May enhance the activity of HIF1A in macrophages by inhibiting the activity of HIF1AN. .

AccessionsENST00000316757.4
O96018