I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 3 studies | 19% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 3 studies | 19% ± 3% |
Insufficient scRNA-seq data for expression of ANKRD31 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| breast | 97% | 33.48 | 444 / 459 | 7% | 0.12 | 78 / 1118 |
| ovary | 100% | 42.08 | 180 / 180 | 3% | 0.04 | 13 / 430 |
| uterus | 99% | 32.85 | 168 / 170 | 2% | 0.04 | 10 / 459 |
| esophagus | 91% | 44.86 | 1317 / 1445 | 7% | 0.13 | 13 / 183 |
| brain | 97% | 29.90 | 2558 / 2642 | 1% | 0.02 | 10 / 705 |
| pancreas | 97% | 21.57 | 318 / 328 | 1% | 0.01 | 1 / 178 |
| adrenal gland | 97% | 39.68 | 249 / 258 | 1% | 0.02 | 2 / 230 |
| prostate | 97% | 26.37 | 238 / 245 | 0% | 0 | 0 / 502 |
| bladder | 95% | 20.29 | 20 / 21 | 2% | 0.04 | 8 / 504 |
| thymus | 95% | 28.09 | 621 / 653 | 1% | 0.02 | 9 / 605 |
| skin | 94% | 21.52 | 1697 / 1809 | 3% | 0.03 | 13 / 472 |
| stomach | 96% | 24.34 | 343 / 359 | 1% | 0.01 | 2 / 286 |
| adipose | 95% | 22.42 | 1148 / 1204 | 0% | 0 | 0 / 0 |
| kidney | 87% | 19.72 | 77 / 89 | 4% | 0.07 | 39 / 901 |
| spleen | 89% | 13.45 | 215 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 85% | 14.84 | 1140 / 1335 | 0% | 0 | 0 / 0 |
| intestine | 79% | 13.07 | 762 / 966 | 1% | 0.01 | 6 / 527 |
| lung | 77% | 12.82 | 444 / 578 | 1% | 0.02 | 16 / 1155 |
| liver | 70% | 9.03 | 158 / 226 | 1% | 0.02 | 6 / 406 |
| heart | 55% | 7.42 | 475 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 28% | 3.63 | 256 / 929 | 0% | 0 | 0 / 0 |
| muscle | 22% | 2.01 | 174 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.02 | 1 / 45 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_1903343 | Biological process | positive regulation of meiotic DNA double-strand break formation |
| GO_0010780 | Biological process | meiotic DNA double-strand break formation involved in reciprocal meiotic recombination |
| GO_0007129 | Biological process | homologous chromosome pairing at meiosis |
| GO_0000785 | Cellular component | chromatin |
| GO_0005634 | Cellular component | nucleus |
| Gene name | ANKRD31 |
| Protein name | Ankyrin repeat domain 31 Ankyrin repeat domain-containing protein 31 Alternative protein ANKRD31 |
| Synonyms | |
| Description | FUNCTION: Required for DNA double-strand breaks (DSBs) formation during meiotic recombination. Regulates the spatial and temporal patterns of pre-DSB recombinosome assembly and recombination activity by acting as a scaffold that anchors REC114 and other factors to specific genomic locations, thereby regulating DSB formation. Plays a key role in recombination in the pseudoautosomal regions of sex chromosomes. . |
| Accessions | Q8N7Z5 D6RJB7 A0A669KAY2 ENST00000506364.6 ENST00000674120.1 L8E6U2 ENST00000274361.3 |
