Insufficient scRNA-seq data for expression of AMTN at single-cell level.
Insufficient scRNA-seq data for expression of AMTN at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 78% | 27.91 | 192 / 245 | 34% | 2.30 | 169 / 502 |
| tonsil | 0% | 0 | 0 / 0 | 80% | 67.76 | 36 / 45 |
| esophagus | 22% | 4.37 | 321 / 1445 | 44% | 39.62 | 81 / 183 |
| lung | 34% | 13.54 | 198 / 578 | 27% | 37.13 | 313 / 1155 |
| uterus | 0% | 0 | 0 / 170 | 39% | 29.66 | 179 / 459 |
| stomach | 32% | 20.72 | 115 / 359 | 2% | 0.11 | 7 / 286 |
| skin | 21% | 6.60 | 374 / 1809 | 2% | 0.11 | 10 / 472 |
| pancreas | 0% | 0 | 0 / 328 | 20% | 2.13 | 36 / 178 |
| eye | 0% | 0 | 0 / 0 | 16% | 3.19 | 13 / 80 |
| breast | 6% | 0.95 | 27 / 459 | 10% | 3.20 | 112 / 1118 |
| bladder | 0% | 0 | 0 / 21 | 14% | 6.13 | 73 / 504 |
| thymus | 7% | 0.74 | 47 / 653 | 7% | 0.56 | 44 / 605 |
| intestine | 0% | 0.04 | 3 / 966 | 4% | 0.49 | 23 / 527 |
| blood vessel | 2% | 0.28 | 21 / 1335 | 0% | 0 | 0 / 0 |
| liver | 0% | 0 | 0 / 226 | 1% | 0.07 | 5 / 406 |
| kidney | 0% | 0 | 0 / 89 | 1% | 0.16 | 10 / 901 |
| brain | 1% | 0.11 | 15 / 2642 | 0% | 0.01 | 2 / 705 |
| adrenal gland | 0% | 0.03 | 1 / 258 | 0% | 6.74 | 1 / 230 |
| ovary | 0% | 0 | 0 / 180 | 1% | 0.03 | 3 / 430 |
| adipose | 1% | 0.11 | 7 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0.03 | 1 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0.01 | 1 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0042475 | Biological process | odontogenesis of dentin-containing tooth |
| GO_0070169 | Biological process | positive regulation of biomineral tissue development |
| GO_0070175 | Biological process | positive regulation of enamel mineralization |
| GO_0007155 | Biological process | cell adhesion |
| GO_0031214 | Biological process | biomineral tissue development |
| GO_0005911 | Cellular component | cell-cell junction |
| GO_0005604 | Cellular component | basement membrane |
| GO_0005788 | Cellular component | endoplasmic reticulum lumen |
| GO_0005576 | Cellular component | extracellular region |
| GO_0031012 | Cellular component | extracellular matrix |
| GO_0005515 | Molecular function | protein binding |
| GO_0003674 | Molecular function | molecular_function |
| Gene name | AMTN |
| Protein name | Amelotin |
| Synonyms | UNQ689/PRO1329 |
| Description | FUNCTION: Is a promoter of calcium phosphate mineralization, playing a critical role in the formation of the compact, mineralized, aprismatic enamel surface layer during the maturation stage of amelogenesis. . |
| Accessions | ENST00000504451.1 [Q6UX39-2] ENST00000339336.9 [Q6UX39-1] Q6UX39 F1T0L8 |