Insufficient scRNA-seq data for expression of AMTN at single-cell level.
Insufficient scRNA-seq data for expression of AMTN at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 78% | 27.91 | 192 / 245 | 34% | 2.30 | 169 / 502 |
tonsil | 0% | 0 | 0 / 0 | 80% | 67.76 | 36 / 45 |
esophagus | 22% | 4.37 | 321 / 1445 | 44% | 39.62 | 81 / 183 |
lung | 34% | 13.54 | 198 / 578 | 27% | 37.13 | 313 / 1155 |
uterus | 0% | 0 | 0 / 170 | 39% | 29.66 | 179 / 459 |
stomach | 32% | 20.72 | 115 / 359 | 2% | 0.11 | 7 / 286 |
skin | 21% | 6.60 | 374 / 1809 | 2% | 0.11 | 10 / 472 |
pancreas | 0% | 0 | 0 / 328 | 20% | 2.13 | 36 / 178 |
eye | 0% | 0 | 0 / 0 | 16% | 3.19 | 13 / 80 |
breast | 6% | 0.95 | 27 / 459 | 10% | 3.20 | 112 / 1118 |
bladder | 0% | 0 | 0 / 21 | 14% | 6.13 | 73 / 504 |
thymus | 7% | 0.74 | 47 / 653 | 7% | 0.56 | 44 / 605 |
intestine | 0% | 0.04 | 3 / 966 | 4% | 0.49 | 23 / 527 |
blood vessel | 2% | 0.28 | 21 / 1335 | 0% | 0 | 0 / 0 |
liver | 0% | 0 | 0 / 226 | 1% | 0.07 | 5 / 406 |
kidney | 0% | 0 | 0 / 89 | 1% | 0.16 | 10 / 901 |
brain | 1% | 0.11 | 15 / 2642 | 0% | 0.01 | 2 / 705 |
adrenal gland | 0% | 0.03 | 1 / 258 | 0% | 6.74 | 1 / 230 |
ovary | 0% | 0 | 0 / 180 | 1% | 0.03 | 3 / 430 |
adipose | 1% | 0.11 | 7 / 1204 | 0% | 0 | 0 / 0 |
muscle | 0% | 0.03 | 1 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0.01 | 1 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0042475 | Biological process | odontogenesis of dentin-containing tooth |
GO_0070169 | Biological process | positive regulation of biomineral tissue development |
GO_0070175 | Biological process | positive regulation of enamel mineralization |
GO_0007155 | Biological process | cell adhesion |
GO_0031214 | Biological process | biomineral tissue development |
GO_0005911 | Cellular component | cell-cell junction |
GO_0005604 | Cellular component | basement membrane |
GO_0005788 | Cellular component | endoplasmic reticulum lumen |
GO_0005576 | Cellular component | extracellular region |
GO_0031012 | Cellular component | extracellular matrix |
GO_0005515 | Molecular function | protein binding |
GO_0003674 | Molecular function | molecular_function |
Gene name | AMTN |
Protein name | Amelotin |
Synonyms | UNQ689/PRO1329 |
Description | FUNCTION: Is a promoter of calcium phosphate mineralization, playing a critical role in the formation of the compact, mineralized, aprismatic enamel surface layer during the maturation stage of amelogenesis. . |
Accessions | ENST00000504451.1 [Q6UX39-2] ENST00000339336.9 [Q6UX39-1] Q6UX39 F1T0L8 |