Insufficient scRNA-seq data for expression of AMELY at single-cell level.
Insufficient scRNA-seq data for expression of AMELY at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| ureter | 0% | 0 | 0 / 0 | 100% | 3.40 | 1 / 1 |
| thymus | 64% | 11.54 | 417 / 653 | 6% | 0.17 | 37 / 605 |
| prostate | 38% | 1.35 | 92 / 245 | 20% | 0.39 | 98 / 502 |
| pancreas | 52% | 3.30 | 169 / 328 | 0% | 0 | 0 / 178 |
| kidney | 47% | 1.99 | 42 / 89 | 0% | 0 | 0 / 901 |
| breast | 38% | 2.63 | 173 / 459 | 0% | 0 | 0 / 1118 |
| stomach | 27% | 1.21 | 96 / 359 | 0% | 0 | 0 / 286 |
| adipose | 20% | 0.77 | 238 / 1204 | 0% | 0 | 0 / 0 |
| esophagus | 13% | 0.38 | 190 / 1445 | 1% | 0.02 | 2 / 183 |
| skin | 9% | 0.29 | 167 / 1809 | 0% | 0.00 | 1 / 472 |
| blood vessel | 8% | 0.21 | 112 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 7% | 0.16 | 55 / 803 | 0% | 0 | 0 / 0 |
| liver | 6% | 0.14 | 13 / 226 | 1% | 0.02 | 3 / 406 |
| lung | 4% | 0.10 | 25 / 578 | 2% | 0.03 | 19 / 1155 |
| brain | 6% | 0.17 | 146 / 2642 | 0% | 0.04 | 1 / 705 |
| intestine | 4% | 0.11 | 42 / 966 | 0% | 0.00 | 1 / 527 |
| adrenal gland | 3% | 0.09 | 8 / 258 | 0% | 0 | 0 / 230 |
| bladder | 0% | 0 | 0 / 21 | 2% | 0.04 | 11 / 504 |
| heart | 2% | 0.04 | 15 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 1% | 0.02 | 8 / 929 | 0% | 0 | 0 / 0 |
| spleen | 1% | 0.02 | 2 / 241 | 0% | 0 | 0 / 0 |
| uterus | 1% | 0.01 | 1 / 170 | 0% | 0.02 | 1 / 459 |
| ovary | 1% | 0.01 | 1 / 180 | 0% | 0 | 0 / 430 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| GO_0070166 | Biological process | enamel mineralization |
| GO_0005576 | Cellular component | extracellular region |
| GO_0062023 | Cellular component | collagen-containing extracellular matrix |
| GO_0030345 | Molecular function | structural constituent of tooth enamel |
| Gene name | AMELY |
| Protein name | Amelogenin, Y isoform |
| Synonyms | AMGY AMGL |
| Description | FUNCTION: Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel. |
| Accessions | ENST00000383036.1 [Q99218-2] ENST00000651267.2 [Q99218-1] Q99218 |