AMDHD2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of AMDHD2 at tissue level.

III. Associated gene sets

GO_0006046Biological processN-acetylglucosamine catabolic process
GO_0006048Biological processUDP-N-acetylglucosamine biosynthetic process
GO_0019262Biological processN-acetylneuraminate catabolic process
GO_0005829Cellular componentcytosol
GO_0005634Cellular componentnucleus
GO_0008448Molecular functionN-acetylglucosamine-6-phosphate deacetylase activity
GO_0047419Molecular functionN-acetylgalactosamine-6-phosphate deacetylase activity
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameAMDHD2
Protein nameN-acetylglucosamine-6-phosphate deacetylase (GlcNAc 6-P deacetylase) (EC 3.5.1.25) (Amidohydrolase domain-containing protein 2)
N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25)
Amidohydrolase domain containing 2
SynonymsCGI-14
DescriptionFUNCTION: Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded. .

FUNCTION: Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway. .

AccessionsENST00000568263.5
A0A3B3IU33
ENST00000302956.8 [Q9Y303-2]
ENST00000413459.7 [Q9Y303-3]
H3BT49
ENST00000293971.11 [Q9Y303-1]
Q9Y303
ENST00000648227.1
H3BSD5
ENST00000563556.1
H3BTE3
H3BTZ6
ENST00000569879.5
ENST00000563633.5
H3BSV9
ENST00000566706.5