ALG8 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006490Biological processoligosaccharide-lipid intermediate biosynthetic process
GO_0018279Biological processprotein N-linked glycosylation via asparagine
GO_0006487Biological processprotein N-linked glycosylation
GO_0006488Biological processdolichol-linked oligosaccharide biosynthetic process
GO_0098553Cellular componentlumenal side of endoplasmic reticulum membrane
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0005515Molecular functionprotein binding
GO_0042283Molecular functiondolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity
GO_0004583Molecular functiondolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity

IV. Literature review

[source]
Gene nameALG8
Protein nameAsparagine-linked glycosylation 8 alpha-13-glucosyltransferase-like protein isoform 2
Alternative protein ALG8
Alpha-1,3-glucosyltransferase (EC 2.4.1.-)
ALG8 alpha-1,3-glucosyltransferase
Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase (EC 2.4.1.265) (Asparagine-linked glycosylation protein 8 homolog) (Dol-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichyl alpha-1,3-glucosyltransferase) (Dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase)
SynonymsHUSSY-02
hCG_1819356
DescriptionFUNCTION: Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol before it is transferred to the nascent peptide (By similarity). Required for PKD1/Polycystin-1 maturation and localization to the plasma membrane of the primary cilia (By similarity). .

AccessionsENST00000376156.7 [Q9BVK2-2]
ENST00000680467.1
A0A7P0TAA1
ENST00000525783.6
ENST00000680580.1
E9PP96
ENST00000679539.1
H0YCV0
ENST00000681225.1
A0A7P0Z4J4
ENST00000299626.10 [Q9BVK2-1]
ENST00000681489.1
ENST00000615266.5
ENST00000525761.3
E9PNE2
ENST00000525755.6
ENST00000680829.1
ENST00000532440.6
E9PKA5
ENST00000680256.1
ENST00000530608.6
A0A7P0T919
A0A7P0T9Y0
ENST00000530454.6
A0A7P0T837
A0A7P0Z449
H0YEE0
A0A7P0T9H4
A0A7P0TAL7
H0YD42
ENST00000679986.1
ENST00000532050.5
ENST00000529139.6
ENST00000679697.1
A0A7P0T9A3
ENST00000532306.6
ENST00000680459.1
A0A7P0TAA8
A0A7P0T8Q8
ENST00000680063.1
E9PP80
ENST00000679497.1
ENST00000680223.1
H0YDD3
ENST00000681221.1
ENST00000680399.1
ENST00000680643.1
ENST00000679874.1
ENST00000680866.1
ENST00000680398.1
ENST00000681765.1
ENST00000526737.6
ENST00000679559.1
A0A7P0T845
ENST00000679648.1
ENST00000681417.1
A0A7P0T9J9
E9PR58
ENST00000680499.1
ENST00000681957.1
ENST00000680797.1
ENST00000530910.6
ENST00000681575.1
A0A0S2Z5N3
ENST00000681723.1
ENST00000680996.1
A0A7P0TB84
ENST00000681699.1
ENST00000679444.1
ENST00000526849.6
H0YDV4
ENST00000681384.1
ENST00000681351.1
Q9BVK2
ENST00000680101.1
ENST00000680761.1
A0A804G6E3
A0A024R5K5
ENST00000680329.1
L8E8S9
A0A7P0T810
A0A7P0TA89
A0A7P0T9F4
E9PK79
ENST00000525870.6
A0A7P0T9Q0
ENST00000527099.2
ENST00000679685.1