Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 4 studies | 40% ± 14% | |
| interneuron | 4 studies | 35% ± 22% | |
| epithelial cell | 3 studies | 20% ± 3% | |
| astrocyte | 3 studies | 24% ± 7% | |
| glutamatergic neuron | 3 studies | 48% ± 8% | |
| hepatocyte | 3 studies | 27% ± 11% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 30% ± 12% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 5927.57 | 2640 / 2642 | 100% | 57.80 | 703 / 705 |
| thymus | 99% | 1752.61 | 649 / 653 | 100% | 27.76 | 602 / 605 |
| liver | 100% | 5810.05 | 225 / 226 | 99% | 42.93 | 401 / 406 |
| prostate | 96% | 1268.84 | 235 / 245 | 99% | 16.75 | 497 / 502 |
| kidney | 99% | 1817.17 | 88 / 89 | 95% | 15.74 | 860 / 901 |
| ovary | 95% | 1228.00 | 171 / 180 | 97% | 18.94 | 419 / 430 |
| uterus | 91% | 970.46 | 155 / 170 | 89% | 12.07 | 410 / 459 |
| adrenal gland | 93% | 1438.47 | 240 / 258 | 84% | 9.08 | 193 / 230 |
| intestine | 78% | 816.98 | 750 / 966 | 94% | 14.47 | 496 / 527 |
| breast | 81% | 818.93 | 374 / 459 | 89% | 13.73 | 998 / 1118 |
| stomach | 76% | 652.30 | 272 / 359 | 91% | 15.58 | 261 / 286 |
| bladder | 71% | 1268.67 | 15 / 21 | 94% | 19.63 | 476 / 504 |
| pancreas | 74% | 587.78 | 242 / 328 | 88% | 9.21 | 157 / 178 |
| lung | 62% | 629.75 | 359 / 578 | 94% | 13.96 | 1085 / 1155 |
| esophagus | 59% | 549.55 | 852 / 1445 | 89% | 14.34 | 162 / 183 |
| skin | 70% | 1047.43 | 1274 / 1809 | 73% | 8.83 | 343 / 472 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 36.47 | 29 / 29 |
| ureter | 0% | 0 | 0 / 0 | 100% | 20.38 | 1 / 1 |
| spleen | 100% | 1163.65 | 240 / 241 | 0% | 0 | 0 / 0 |
| muscle | 99% | 3037.81 | 794 / 803 | 0% | 0 | 0 / 0 |
| heart | 85% | 1301.74 | 732 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 81% | 8.99 | 65 / 80 |
| adipose | 79% | 862.09 | 956 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 73% | 11.59 | 33 / 45 |
| blood vessel | 61% | 497.70 | 811 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 29% | 610.47 | 269 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006536 | Biological process | glutamate metabolic process |
| GO_0051932 | Biological process | synaptic transmission, GABAergic |
| GO_0009450 | Biological process | gamma-aminobutyric acid catabolic process |
| GO_0006105 | Biological process | succinate metabolic process |
| GO_0009791 | Biological process | post-embryonic development |
| GO_0007417 | Biological process | central nervous system development |
| GO_0045202 | Cellular component | synapse |
| GO_0005759 | Cellular component | mitochondrial matrix |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0004777 | Molecular function | succinate-semialdehyde dehydrogenase (NAD+) activity |
| GO_0042802 | Molecular function | identical protein binding |
| Gene name | ALDH5A1 |
| Protein name | Succinate-semialdehyde dehydrogenase, mitochondrial (EC 1.2.1.24) (Aldehyde dehydrogenase family 5 member A1) (NAD(+)-dependent succinic semialdehyde dehydrogenase) Succinate semialdehyde dehydrogenase (EC 1.2.1.24) Succinate-semialdehyde dehydrogenase, mitochondrial (EC 1.2.1.24) (NAD(+)-dependent succinic semialdehyde dehydrogenase) Aldehyde dehydrogenase 5 family member A1 Succinate-semialdehyde dehydrogenase (EC 1.2.1.24) |
| Synonyms | SSADH |
| Description | FUNCTION: Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). . FUNCTION: Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). . FUNCTION: Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). . FUNCTION: Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). . FUNCTION: Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). . |
| Accessions | ENST00000491546.5 X5DNC0 ENST00000672557.1 X5D8T4 C9J8Q5 ENST00000672652.1 X5DQN2 A0A5F9ZH05 ENST00000357578.8 [P51649-1] Q8N3W7 A0A5F9ZH98 ENST00000348925.2 [P51649-2] ENST00000672352.1 P51649 X5D299 A0A5F9ZI23 |
