AKR7A3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006081Biological processcellular aldehyde metabolic process
GO_0070062Cellular componentextracellular exosome
GO_0005829Cellular componentcytosol
GO_0005794Cellular componentGolgi apparatus
GO_0005737Cellular componentcytoplasm
GO_0004033Molecular functionaldo-keto reductase (NADPH) activity
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding
GO_0009055Molecular functionelectron transfer activity

IV. Literature review

[source]
Gene nameAKR7A3
Protein nameAflatoxin B1 aldehyde reductase member 3 (EC 1.-.-.-) (AFB1 aldehyde reductase 2) (AFB1-AR 2)
SynonymsAFAR2
DescriptionFUNCTION: Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen. .

AccessionsO95154
ENST00000361640.5