AKR1B10 | OmnibusX

Name	Number of supported studies	Average coverage
enterocyte	5 studies	38% ± 9%	Explore
epithelial cell	4 studies	26% ± 7%	Explore

Name	Number of supported studies	Average coverage
intestine	3 studies	17% ± 1%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
stomach	84%	19473.18	303 / 359	49%	111.28	140 / 286
bladder	100%	4675.57	21 / 21	31%	141.27	157 / 504
liver	52%	1843.85	118 / 226	75%	914.83	304 / 406
esophagus	42%	5373.31	606 / 1445	77%	446.94	140 / 183
ureter	0%	0	0 / 0	100%	42.67	1 / 1
intestine	54%	3321.62	517 / 966	43%	62.19	225 / 527
tonsil	0%	0	0 / 0	71%	148.19	32 / 45
pancreas	7%	22.79	22 / 328	58%	88.64	104 / 178
adrenal gland	64%	404.14	164 / 258	1%	0.60	3 / 230
kidney	51%	806.96	45 / 89	14%	134.39	128 / 901
muscle	61%	253.46	489 / 803	0%	0	0 / 0
skin	55%	378.50	995 / 1809	5%	5.47	24 / 472
lung	3%	30.59	20 / 578	48%	405.35	560 / 1155
uterus	4%	180.28	6 / 170	42%	154.40	192 / 459
thymus	10%	29.57	66 / 653	5%	10.13	28 / 605
prostate	13%	89.81	32 / 245	0%	0	0 / 502
blood vessel	8%	23.83	112 / 1335	0%	0	0 / 0
breast	3%	16.72	12 / 459	5%	6.45	59 / 1118
ovary	3%	6.59	5 / 180	1%	0.72	6 / 430
adipose	4%	16.11	48 / 1204	0%	0	0 / 0
peripheral blood	1%	12.56	9 / 929	0%	0	0 / 0
heart	1%	1.85	6 / 861	0%	0	0 / 0
spleen	0%	1.03	1 / 241	0%	0	0 / 0
brain	0%	0.10	1 / 2642	0%	0	0 / 705
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0016488	Biological process	farnesol catabolic process
GO_0044597	Biological process	daunorubicin metabolic process
GO_0044598	Biological process	doxorubicin metabolic process
GO_0001523	Biological process	retinoid metabolic process
GO_0042572	Biological process	retinol metabolic process
GO_0110095	Biological process	cellular detoxification of aldehyde
GO_0005576	Cellular component	extracellular region
GO_0005739	Cellular component	mitochondrion
GO_0005764	Cellular component	lysosome
GO_0005829	Cellular component	cytosol
GO_0047655	Molecular function	allyl-alcohol dehydrogenase activity
GO_0047718	Molecular function	indanol dehydrogenase activity
GO_0004032	Molecular function	aldose reductase (NADPH) activity
GO_0004033	Molecular function	aldo-keto reductase (NADPH) activity
GO_0001758	Molecular function	retinal dehydrogenase activity
GO_0052650	Molecular function	all-trans-retinol dehydrogenase (NADP+) activity
GO_0008106	Molecular function	alcohol dehydrogenase (NADP+) activity
GO_0045550	Molecular function	geranylgeranyl reductase activity
GO_0005515	Molecular function	protein binding

Gene name	AKR1B10
Protein name	Aldo-keto reductase family 1 member B10 (EC 1.1.1.300) (EC 1.1.1.54) (ARL-1) (Aldose reductase-like) (Aldose reductase-related protein) (ARP) (hARP) (Small intestine reductase) (SI reductase)
Synonyms	AKR1B11
Description	FUNCTION: Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols . Displays strong enzymatic activity toward all-trans-retinal, 9-cis-retinal, and 13-cis-retinal . Plays a critical role in detoxifying dietary and lipid-derived unsaturated carbonyls, such as crotonaldehyde, 4-hydroxynonenal, trans-2-hexenal, trans-2,4-hexadienal and their glutathione-conjugates carbonyls (GS-carbonyls) . Displays no reductase activity towards glucose . .
Accessions	O60218 ENST00000359579.5

AKR1B10 report