AKAP3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of AKAP3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of AKAP3 at tissue level.

III. Associated gene sets

GO_0008104Biological processprotein localization
GO_0007178Biological processcell surface receptor protein serine/threonine kinase signaling pathway
GO_0007340Biological processacrosome reaction
GO_0007338Biological processsingle fertilization
GO_0001835Biological processblastocyst hatching
GO_0035686Cellular componentsperm fibrous sheath
GO_0097225Cellular componentsperm midpiece
GO_0097228Cellular componentsperm principal piece
GO_0001669Cellular componentacrosomal vesicle
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0051018Molecular functionprotein kinase A binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameAKAP3
Protein nameA-kinase anchor protein 3 (AKAP-3) (A-kinase anchor protein 110 kDa) (AKAP 110) (Cancer/testis antigen 82) (CT82) (Fibrous sheath protein of 95 kDa) (FSP95) (Fibrousheathin I) (Fibrousheathin-1) (Protein kinase A-anchoring protein 3) (PRKA3) (Sperm oocyte-binding protein)
A-kinase anchoring protein 3
SynonymsAKAP110
SOB1
DescriptionFUNCTION: Has a role in the maintenance of acrosome structure . May function as a regulator of both spermatozoa motility and head-associated functions such as capacitation and the acrosome reaction. .

AccessionsENST00000228850.6
ENST00000545990.6
ENST00000540967.5
ENST00000536414.3
F5H7P4
F5H2S4
O75969