AK1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0046940Biological processnucleoside monophosphate phosphorylation
GO_0009142Biological processnucleoside triphosphate biosynthetic process
GO_0046033Biological processAMP metabolic process
GO_0006172Biological processADP biosynthetic process
GO_0046034Biological processATP metabolic process
GO_0015949Biological processnucleobase-containing small molecule interconversion
GO_0001520Cellular componentouter dense fiber
GO_0070062Cellular componentextracellular exosome
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0004017Molecular functionadenylate kinase activity
GO_0004550Molecular functionnucleoside diphosphate kinase activity
GO_0046899Molecular functionnucleoside triphosphate adenylate kinase activity
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameAK1
Protein nameAdenylate kinase isoenzyme 1 (AK 1) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 1) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase) (Myokinase)
Adenylate kinase isoenzyme 1 (AK 1) (EC 2.7.4.10) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 1) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase) (Myokinase)
Adenylate kinase 1
SynonymsHTL-S-58j
hCG_2039407
DescriptionFUNCTION: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP . Exhibits nucleoside diphosphate kinase activity, catalyzing the production of ATP, CTP, GTP, UTP, dATP, dCTP, dGTP and dTTP from the corresponding diphosphate substrates with either ATP or GTP as phosphate donor . Also catalyzes at a very low rate the synthesis of thiamine triphosphate (ThTP) from thiamine diphosphate (ThDP) and ADP (By similarity). .

FUNCTION: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. .

FUNCTION: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. .

AccessionsENST00000550992.1
ENST00000373156.5
ENST00000550143.5
ENST00000644144.2
Q6FGX9
ENST00000223836.10
P00568
F8VRY5
H0YID2
Q5T9B7