AGXT | OmnibusX

Name	Number of supported studies	Average coverage
hepatocyte	6 studies	76% ± 23%	Explore
endothelial cell	3 studies	30% ± 9%	Explore

Name	Number of supported studies	Average coverage
liver	3 studies	49% ± 17%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	107926.43	226 / 226	96%	710.10	388 / 406
kidney	98%	543.00	87 / 89	30%	1.37	269 / 901
spleen	100%	263.52	241 / 241	0%	0	0 / 0
adrenal gland	80%	26.43	206 / 258	13%	0.84	30 / 230
intestine	55%	24.83	536 / 966	28%	1.31	149 / 527
adipose	76%	40.19	915 / 1204	0%	0	0 / 0
breast	70%	33.80	321 / 459	4%	0.53	41 / 1118
stomach	49%	7.69	175 / 359	22%	0.49	62 / 286
pancreas	52%	9.94	169 / 328	13%	0.77	23 / 178
prostate	59%	11.58	145 / 245	2%	0.02	8 / 502
peripheral blood	47%	139.37	436 / 929	0%	0	0 / 0
bladder	33%	3.90	7 / 21	11%	0.27	55 / 504
uterus	36%	6.87	61 / 170	7%	0.35	34 / 459
lung	39%	7.21	226 / 578	4%	0.16	43 / 1155
esophagus	33%	7.14	477 / 1445	8%	0.18	14 / 183
ovary	39%	5.58	71 / 180	1%	0.26	3 / 430
skin	28%	6.69	513 / 1809	4%	0.31	17 / 472
thymus	30%	6.08	199 / 653	0%	0.02	3 / 605
blood vessel	26%	6.77	350 / 1335	0%	0	0 / 0
heart	25%	5.36	216 / 861	0%	0	0 / 0
muscle	21%	2.80	171 / 803	0%	0	0 / 0
brain	18%	2.63	473 / 2642	2%	0.06	12 / 705
eye	0%	0	0 / 0	15%	0.25	12 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007219	Biological process	Notch signaling pathway
GO_0046724	Biological process	oxalic acid secretion
GO_0019265	Biological process	glycine biosynthetic process, by transamination of glyoxylate
GO_0042853	Biological process	L-alanine catabolic process
GO_0046487	Biological process	glyoxylate metabolic process
GO_0019448	Biological process	L-cysteine catabolic process
GO_0009436	Biological process	glyoxylate catabolic process
GO_0006563	Biological process	L-serine metabolic process
GO_0005777	Cellular component	peroxisome
GO_0005829	Cellular component	cytosol
GO_0005782	Cellular component	peroxisomal matrix
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0042803	Molecular function	protein homodimerization activity
GO_0030170	Molecular function	pyridoxal phosphate binding
GO_0042802	Molecular function	identical protein binding
GO_0008453	Molecular function	alanine-glyoxylate transaminase activity
GO_0016597	Molecular function	amino acid binding
GO_0004760	Molecular function	serine-pyruvate transaminase activity
GO_0008483	Molecular function	transaminase activity
GO_0005515	Molecular function	protein binding

Gene name	AGXT
Protein name	Alanine--glyoxylate aminotransferase (AGT) (SPT) (EC 2.6.1.44) (EC 2.6.1.51) (Serine--pyruvate aminotransferase) Alanine--glyoxylate aminotransferase (AGT) (EC 2.6.1.44) (Serine--pyruvate aminotransferase) (SPT) (EC 2.6.1.51)
Synonyms	AGT1 SPAT
Description	FUNCTION: Peroxisomal aminotransferase that catalyzes the transamination of glyoxylate to glycine and contributes to the glyoxylate detoxification . Also catalyzes the transamination between L-serine and pyruvate and contributes to gluconeogenesis from the L-serine metabolism . .
Accessions	ENST00000307503.4 A2V838 P21549

AGXT report