AGBL2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of AGBL2 at tissue level.

III. Associated gene sets

GO_0006508Biological processproteolysis
GO_0035610Biological processprotein side chain deglutamylation
GO_0005814Cellular componentcentriole
GO_0036064Cellular componentciliary basal body
GO_0005829Cellular componentcytosol
GO_0005515Molecular functionprotein binding
GO_0008270Molecular functionzinc ion binding
GO_0004181Molecular functionmetallocarboxypeptidase activity

IV. Literature review

[source]
Gene nameAGBL2
Protein nameCytosolic carboxypeptidase 2 (EC 3.4.17.-) (ATP/GTP-binding protein-like 2) (Protein deglutamylase CCP2)
AGBL carboxypeptidase 2
Cytosolic carboxypeptidase 2 (ATP/GTP-binding protein-like 2) (Protein deglutamylase CCP2)
SynonymshCG_2042982
CCP2
DescriptionFUNCTION: Metallocarboxypeptidase that mediates deglutamylation of tubulin and non-tubulin target proteins. Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of tubulin protein. Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate. Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of non-tubulin proteins such as MYLK. .

AccessionsQ5U5Z8
ENST00000530577.5
ENST00000645431.2 [Q5U5Z8-1]
ENST00000532595.5
ENST00000525123.6 [Q5U5Z8-1]
ENST00000530969.1
J9JIH1
ENST00000528244.5
E9PS54
F6U0I4
ENST00000529154.5
ENST00000528609.5
E9PJH3
A0A140VKH9
E9PR59
E9PRJ1
E9PI49
ENST00000528632.5