AFP report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of AFP at tissue level.

III. Associated gene sets

GO_0006810Biological processtransport
GO_0042448Biological processprogesterone metabolic process
GO_0001542Biological processovulation from ovarian follicle
GO_0005615Cellular componentextracellular space
GO_0005788Cellular componentendoplasmic reticulum lumen
GO_0005737Cellular componentcytoplasm
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding
GO_0036094Molecular functionsmall molecule binding

IV. Literature review

[source]
Gene nameAFP
Protein nameAlpha-fetoprotein (Alpha-1-fetoprotein) (Alpha-fetoglobulin)
SynonymsHPAFP
DescriptionFUNCTION: Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties.

AccessionsP02771
ENST00000395792.7
J3KMX3
ENST00000226359.2