Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell of proximal tubule | 3 studies | 51% ± 22% | |
| enterocyte | 3 studies | 36% ± 16% | |
| epithelial cell | 3 studies | 27% ± 2% |
Insufficient scRNA-seq data for expression of AFP at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 99% | 170.08 | 224 / 226 | 84% | 550.00 | 341 / 406 |
| kidney | 92% | 66.90 | 82 / 89 | 7% | 0.23 | 62 / 901 |
| adrenal gland | 81% | 18.52 | 208 / 258 | 9% | 2.33 | 20 / 230 |
| ovary | 76% | 13.86 | 137 / 180 | 1% | 0.06 | 6 / 430 |
| breast | 48% | 31.81 | 221 / 459 | 24% | 3.08 | 273 / 1118 |
| stomach | 42% | 2.92 | 152 / 359 | 12% | 1.04 | 35 / 286 |
| brain | 37% | 4.78 | 985 / 2642 | 5% | 0.15 | 37 / 705 |
| uterus | 36% | 5.98 | 62 / 170 | 5% | 0.58 | 24 / 459 |
| pancreas | 33% | 1.77 | 108 / 328 | 4% | 0.14 | 8 / 178 |
| blood vessel | 35% | 5.08 | 470 / 1335 | 0% | 0 | 0 / 0 |
| heart | 33% | 2.81 | 285 / 861 | 0% | 0 | 0 / 0 |
| esophagus | 21% | 1.37 | 307 / 1445 | 9% | 13.42 | 16 / 183 |
| bladder | 19% | 1.52 | 4 / 21 | 6% | 0.44 | 32 / 504 |
| skin | 20% | 1.52 | 370 / 1809 | 2% | 0.22 | 10 / 472 |
| intestine | 14% | 1.05 | 133 / 966 | 6% | 1.76 | 31 / 527 |
| muscle | 19% | 1.30 | 149 / 803 | 0% | 0 | 0 / 0 |
| adipose | 18% | 1.03 | 211 / 1204 | 0% | 0 | 0 / 0 |
| lung | 9% | 0.58 | 54 / 578 | 8% | 9.09 | 88 / 1155 |
| prostate | 6% | 0.28 | 14 / 245 | 6% | 0.18 | 30 / 502 |
| thymus | 6% | 0.31 | 38 / 653 | 1% | 0.02 | 4 / 605 |
| peripheral blood | 5% | 0.40 | 46 / 929 | 0% | 0 | 0 / 0 |
| spleen | 1% | 0.22 | 2 / 241 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006810 | Biological process | transport |
| GO_0042448 | Biological process | progesterone metabolic process |
| GO_0001542 | Biological process | ovulation from ovarian follicle |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005788 | Cellular component | endoplasmic reticulum lumen |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005515 | Molecular function | protein binding |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0036094 | Molecular function | small molecule binding |
| Gene name | AFP |
| Protein name | Alpha-fetoprotein (Alpha-1-fetoprotein) (Alpha-fetoglobulin) |
| Synonyms | HPAFP |
| Description | FUNCTION: Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. |
| Accessions | P02771 ENST00000395792.7 J3KMX3 ENST00000226359.2 |