I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 4 studies | 21% ± 6% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 4 studies | 21% ± 6% |
Insufficient scRNA-seq data for expression of AFG2B at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 837.70 | 1445 / 1445 | 100% | 13.79 | 183 / 183 |
| intestine | 100% | 713.68 | 966 / 966 | 100% | 13.66 | 527 / 527 |
| stomach | 100% | 491.09 | 359 / 359 | 100% | 13.40 | 286 / 286 |
| breast | 100% | 741.08 | 459 / 459 | 100% | 11.24 | 1116 / 1118 |
| pancreas | 100% | 441.72 | 327 / 328 | 100% | 9.61 | 178 / 178 |
| bladder | 100% | 809.76 | 21 / 21 | 100% | 12.70 | 502 / 504 |
| prostate | 100% | 632.26 | 245 / 245 | 100% | 8.83 | 500 / 502 |
| ovary | 100% | 889.94 | 180 / 180 | 100% | 9.65 | 428 / 430 |
| liver | 100% | 432.51 | 226 / 226 | 100% | 8.93 | 404 / 406 |
| thymus | 100% | 671.40 | 653 / 653 | 100% | 9.96 | 602 / 605 |
| uterus | 100% | 817.22 | 170 / 170 | 99% | 14.24 | 456 / 459 |
| lung | 99% | 500.25 | 574 / 578 | 100% | 10.83 | 1155 / 1155 |
| skin | 100% | 1121.26 | 1809 / 1809 | 99% | 10.44 | 466 / 472 |
| kidney | 100% | 496.44 | 89 / 89 | 98% | 8.53 | 882 / 901 |
| brain | 98% | 433.16 | 2577 / 2642 | 100% | 11.34 | 705 / 705 |
| adrenal gland | 100% | 597.41 | 258 / 258 | 96% | 6.95 | 220 / 230 |
| adipose | 100% | 688.44 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 10.53 | 29 / 29 |
| muscle | 100% | 743.68 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 597.87 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 11.95 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 7.24 | 1 / 1 |
| blood vessel | 100% | 577.86 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| heart | 96% | 385.95 | 827 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 93% | 559.24 | 861 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 93% | 5.63 | 74 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0042273 | Biological process | ribosomal large subunit biogenesis |
| GO_0005819 | Cellular component | spindle |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_1990275 | Molecular function | preribosome binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0016887 | Molecular function | ATP hydrolysis activity |
| GO_0005524 | Molecular function | ATP binding |
| Gene name | AFG2B |
| Protein name | ATPase family gene 2 protein homolog B (EC 3.6.4.10) (AFG2 AAA ATPase homolog B) (Ribosome biogenesis protein SPATA5L1) (Spermatogenesis-associated protein 5-like protein 1) Spermatogenesis associated 5 like 1 |
| Synonyms | SPATA5L1 |
| Description | FUNCTION: ATP-dependent chaperone, which plays an essential role in the cytoplasmic maturation steps of pre-60S ribosomal particles by promoting the release of shuttling protein RSL24D1/RLP24 from the pre-ribosomal particles . Acts together with AFG2A, AIRIM and CINP . . |
| Accessions | ENST00000305560.11 [Q9BVQ7-1] Q9BVQ7 ENST00000531624.1 ENST00000525552.1 ENST00000531970.5 [Q9BVQ7-2] H0YL79 H0YCA5 |
