Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| astrocyte | 9 studies | 32% ± 17% | |
| GABAergic neuron | 5 studies | 42% ± 19% | |
| glutamatergic neuron | 5 studies | 45% ± 21% | |
| oligodendrocyte | 5 studies | 26% ± 11% | |
| cardiac muscle cell | 4 studies | 18% ± 1% | |
| oligodendrocyte precursor cell | 4 studies | 28% ± 7% | |
| adipocyte | 4 studies | 19% ± 3% | |
| interneuron | 4 studies | 42% ± 21% | |
| epithelial cell | 3 studies | 22% ± 8% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 5 studies | 41% ± 16% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 295.52 | 2639 / 2642 | 100% | 3.83 | 702 / 705 |
| kidney | 100% | 321.16 | 89 / 89 | 96% | 2.80 | 867 / 901 |
| thymus | 100% | 242.29 | 653 / 653 | 95% | 2.07 | 577 / 605 |
| breast | 100% | 208.98 | 458 / 459 | 96% | 2.27 | 1068 / 1118 |
| prostate | 100% | 192.02 | 244 / 245 | 89% | 1.97 | 448 / 502 |
| adrenal gland | 100% | 379.10 | 258 / 258 | 89% | 2.02 | 204 / 230 |
| bladder | 100% | 173.57 | 21 / 21 | 88% | 1.71 | 442 / 504 |
| intestine | 100% | 198.39 | 965 / 966 | 87% | 1.76 | 459 / 527 |
| lung | 99% | 183.28 | 575 / 578 | 87% | 1.59 | 1008 / 1155 |
| esophagus | 100% | 162.74 | 1442 / 1445 | 87% | 1.51 | 159 / 183 |
| pancreas | 99% | 142.85 | 325 / 328 | 87% | 1.52 | 155 / 178 |
| stomach | 100% | 189.44 | 358 / 359 | 85% | 1.66 | 244 / 286 |
| uterus | 100% | 154.93 | 170 / 170 | 85% | 1.68 | 390 / 459 |
| skin | 100% | 229.18 | 1800 / 1809 | 84% | 1.90 | 397 / 472 |
| liver | 100% | 175.77 | 225 / 226 | 73% | 1.20 | 295 / 406 |
| ovary | 100% | 182.05 | 180 / 180 | 59% | 0.95 | 252 / 430 |
| spleen | 100% | 213.02 | 241 / 241 | 0% | 0 | 0 / 0 |
| adipose | 100% | 213.30 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 100% | 199.02 | 799 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 99% | 150.79 | 1324 / 1335 | 0% | 0 | 0 / 0 |
| heart | 96% | 261.67 | 829 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 90% | 1.45 | 26 / 29 |
| eye | 0% | 0 | 0 / 0 | 83% | 1.86 | 66 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 82% | 1.41 | 37 / 45 |
| peripheral blood | 53% | 98.51 | 495 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007005 | Biological process | mitochondrion organization |
| GO_0035694 | Biological process | mitochondrial protein catabolic process |
| GO_0006123 | Biological process | mitochondrial electron transport, cytochrome c to oxygen |
| GO_0031966 | Cellular component | mitochondrial membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0005515 | Molecular function | protein binding |
| GO_0016887 | Molecular function | ATP hydrolysis activity |
| GO_0005524 | Molecular function | ATP binding |
| Gene name | AFG1L |
| Protein name | AFG1-like ATPase (Lactation elevated protein 1) (EC 3.6.-.-) (Protein AFG1 homolog) AFG1 like ATPase |
| Synonyms | LACE1 AFG1 |
| Description | FUNCTION: Putative mitochondrial ATPase. Plays a role in mitochondrial morphology and mitochondrial protein metabolism. Promotes degradation of excess nuclear-encoded complex IV subunits (COX4I1, COX5A and COX6A1) and normal activity of complexes III and IV of the respiratory chain . Mediates mitochondrial translocation of TP53 and its transcription-independent apoptosis in response to genotoxic stress . . |
| Accessions | H7C448 ENST00000437715.1 A6ZJA2 ENST00000368977.9 ENST00000421954.5 H0Y5F4 Q8WV93 ENST00000431865.1 |
