Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 13 studies | 25% ± 12% | |
oligodendrocyte precursor cell | 13 studies | 42% ± 18% | |
fibroblast | 11 studies | 22% ± 5% | |
GABAergic neuron | 9 studies | 42% ± 20% | |
interneuron | 7 studies | 41% ± 21% | |
glutamatergic neuron | 5 studies | 40% ± 11% | |
vein endothelial cell | 5 studies | 24% ± 13% | |
epithelial cell | 4 studies | 20% ± 4% | |
neuron | 4 studies | 35% ± 11% | |
pericyte | 4 studies | 31% ± 18% | |
adipocyte | 4 studies | 18% ± 1% | |
smooth muscle cell | 4 studies | 18% ± 2% | |
GABAergic interneuron | 3 studies | 37% ± 4% | |
astrocyte | 3 studies | 29% ± 14% | |
extravillous trophoblast | 3 studies | 38% ± 22% | |
mesothelial cell | 3 studies | 27% ± 2% | |
Mueller cell | 3 studies | 17% ± 1% | |
endothelial cell of vascular tree | 3 studies | 25% ± 10% | |
goblet cell | 3 studies | 28% ± 6% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 8 studies | 32% ± 14% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 3669.66 | 1442 / 1445 | 100% | 6.01 | 183 / 183 |
intestine | 100% | 4572.94 | 966 / 966 | 98% | 4.23 | 518 / 527 |
ovary | 100% | 2255.69 | 180 / 180 | 97% | 3.94 | 416 / 430 |
breast | 100% | 3366.47 | 459 / 459 | 96% | 4.19 | 1077 / 1118 |
lung | 100% | 2776.73 | 576 / 578 | 96% | 4.03 | 1112 / 1155 |
stomach | 95% | 1944.78 | 340 / 359 | 98% | 5.33 | 281 / 286 |
brain | 96% | 1742.81 | 2538 / 2642 | 96% | 5.18 | 679 / 705 |
thymus | 100% | 2696.48 | 653 / 653 | 92% | 3.47 | 554 / 605 |
prostate | 100% | 2675.69 | 244 / 245 | 89% | 2.22 | 449 / 502 |
uterus | 100% | 4361.86 | 170 / 170 | 88% | 2.90 | 405 / 459 |
skin | 97% | 2756.70 | 1760 / 1809 | 83% | 3.75 | 394 / 472 |
bladder | 100% | 4807.38 | 21 / 21 | 77% | 2.34 | 389 / 504 |
kidney | 96% | 1323.36 | 85 / 89 | 76% | 2.48 | 685 / 901 |
pancreas | 60% | 510.37 | 196 / 328 | 96% | 4.54 | 171 / 178 |
adrenal gland | 95% | 993.68 | 245 / 258 | 45% | 0.87 | 104 / 230 |
adipose | 100% | 4089.45 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 4283.36 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 94% | 1024.33 | 227 / 241 | 0% | 0 | 0 / 0 |
heart | 85% | 1567.47 | 732 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 84% | 3.74 | 38 / 45 |
eye | 0% | 0 | 0 / 0 | 76% | 1.31 | 61 / 80 |
muscle | 50% | 528.98 | 399 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 28% | 0.39 | 8 / 29 |
liver | 2% | 19.16 | 5 / 226 | 19% | 0.45 | 79 / 406 |
peripheral blood | 10% | 69.90 | 92 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0001725 | Cellular component | stress fiber |
GO_0015629 | Cellular component | actin cytoskeleton |
GO_0005829 | Cellular component | cytosol |
GO_0005925 | Cellular component | focal adhesion |
GO_0042169 | Molecular function | SH2 domain binding |
GO_0003779 | Molecular function | actin binding |
GO_0017124 | Molecular function | SH3 domain binding |
Gene name | AFAP1 |
Protein name | Actin filament-associated protein 1 (110 kDa actin filament-associated protein) (AFAP-110) Actin filament associated protein 1 |
Synonyms | AFAP |
Description | FUNCTION: Can cross-link actin filaments into both network and bundle structures (By similarity). May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells. . |
Accessions | A0A087X177 ENST00000382543.4 [Q8N556-2] ENST00000420658.6 [Q8N556-2] ENST00000360265.9 [Q8N556-1] Q8N556 ENST00000358461.6 [Q8N556-1] ENST00000614385.1 |