ADO report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ADO at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ADO at tissue level.

III. Associated gene sets

GO_0071456Biological processcellular response to hypoxia
GO_0005829Cellular componentcytosol
GO_0005506Molecular functioniron ion binding
GO_0005515Molecular functionprotein binding
GO_0047800Molecular functioncysteamine dioxygenase activity

IV. Literature review

[source]
Gene nameADO
Protein name2-aminoethanethiol dioxygenase
2-aminoethanethiol dioxygenase (EC 1.13.11.19) (Cysteamine dioxygenase)
SynonymsC10orf22
DescriptionFUNCTION: Plays a vital role in regulating thiol metabolism and preserving oxygen homeostasis by oxidizing the sulfur of cysteamine and N-terminal cysteine-containing proteins to their corresponding sulfinic acids using O2 as a cosubstrate . Catalyzes the oxidation of cysteamine (2-aminoethanethiol) to hypotaurine . Catalyzes the oxidation of regulators of G-protein signaling 4 (RGS4) and 5 (RGS5) and interleukin-32 (IL32) . .

AccessionsENST00000710287.1
A0AA34QVG9
Q96SZ5
ENST00000373783.3