ADD2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0051016Biological processbarbed-end actin filament capping
GO_0030097Biological processhemopoiesis
GO_0032092Biological processpositive regulation of protein binding
GO_0065003Biological processprotein-containing complex assembly
GO_0051017Biological processactin filament bundle assembly
GO_0030036Biological processactin cytoskeleton organization
GO_0050900Biological processleukocyte migration
GO_0050901Biological processleukocyte tethering or rolling
GO_0007416Biological processsynapse assembly
GO_0005856Cellular componentcytoskeleton
GO_0005886Cellular componentplasma membrane
GO_0031410Cellular componentcytoplasmic vesicle
GO_0044853Cellular componentplasma membrane raft
GO_0005829Cellular componentcytosol
GO_0014069Cellular componentpostsynaptic density
GO_0008290Cellular componentF-actin capping protein complex
GO_0042803Molecular functionprotein homodimerization activity
GO_0030507Molecular functionspectrin binding
GO_0005200Molecular functionstructural constituent of cytoskeleton
GO_0019901Molecular functionprotein kinase binding
GO_0051015Molecular functionactin filament binding
GO_0046982Molecular functionprotein heterodimerization activity
GO_0005516Molecular functioncalmodulin binding
GO_0046983Molecular functionprotein dimerization activity
GO_0003779Molecular functionactin binding

IV. Literature review

[source]
Gene nameADD2
Protein nameADD2 protein
Beta-adducin (Erythrocyte adducin subunit beta)
Adducin 2
SynonymsADDB
DescriptionFUNCTION: Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to the erythrocyte membrane receptor SLC2A1/GLUT1 and may therefore provide a link between the spectrin cytoskeleton to the plasma membrane. Binds to calmodulin. Calmodulin binds preferentially to the beta subunit. .

AccessionsC9J080
ENST00000447731.6
ENST00000407644.6 [P35612-1]
ENST00000413157.6 [P35612-2]
C9JTM0
ENST00000425976.5
ENST00000415348.5
Q05DK5
ENST00000430656.5 [P35612-9]
ENST00000456320.7
ENST00000522886.5
ENST00000403045.6 [P35612-1]
A0A1C7CYY0
P35612
ENST00000264436.9 [P35612-1]
C9JJK3
C9J299
ENST00000355733.7 [P35612-3]