Name | Number of supported studies | Average coverage | |
---|---|---|---|
pericyte | 19 studies | 32% ± 17% | |
smooth muscle cell | 12 studies | 24% ± 6% | |
fibroblast | 9 studies | 19% ± 2% | |
retinal ganglion cell | 6 studies | 31% ± 15% | |
endothelial cell | 5 studies | 26% ± 6% | |
GABAergic neuron | 4 studies | 38% ± 15% | |
astrocyte | 4 studies | 25% ± 5% | |
glutamatergic neuron | 4 studies | 46% ± 20% | |
neuron | 3 studies | 21% ± 7% | |
myeloid cell | 3 studies | 18% ± 2% | |
alveolar macrophage | 3 studies | 21% ± 5% | |
interneuron | 3 studies | 38% ± 19% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 5 studies | 33% ± 15% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 99% | 2842.66 | 1432 / 1445 | 99% | 31.81 | 182 / 183 |
intestine | 99% | 2305.46 | 961 / 966 | 98% | 20.82 | 517 / 527 |
lung | 100% | 3490.06 | 578 / 578 | 97% | 20.36 | 1116 / 1155 |
breast | 100% | 6439.62 | 459 / 459 | 94% | 16.38 | 1049 / 1118 |
ovary | 100% | 5576.39 | 180 / 180 | 93% | 15.96 | 401 / 430 |
skin | 100% | 3468.15 | 1808 / 1809 | 92% | 18.29 | 436 / 472 |
uterus | 100% | 5199.39 | 170 / 170 | 92% | 18.42 | 423 / 459 |
bladder | 100% | 2928.29 | 21 / 21 | 90% | 15.56 | 455 / 504 |
brain | 91% | 2028.28 | 2417 / 2642 | 98% | 16.20 | 688 / 705 |
stomach | 86% | 1705.69 | 309 / 359 | 99% | 22.88 | 284 / 286 |
prostate | 99% | 3069.72 | 242 / 245 | 78% | 7.92 | 392 / 502 |
thymus | 100% | 3412.52 | 651 / 653 | 73% | 6.44 | 440 / 605 |
adrenal gland | 78% | 1090.76 | 202 / 258 | 68% | 9.40 | 156 / 230 |
pancreas | 45% | 455.29 | 146 / 328 | 94% | 12.97 | 167 / 178 |
kidney | 70% | 1258.21 | 62 / 89 | 68% | 11.17 | 613 / 901 |
adipose | 100% | 7620.00 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 3553.11 | 1334 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 1851.90 | 240 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 96% | 23.14 | 43 / 45 |
heart | 92% | 1618.10 | 796 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 91% | 12.26 | 73 / 80 |
lymph node | 0% | 0 | 0 / 0 | 86% | 18.50 | 25 / 29 |
muscle | 47% | 555.93 | 376 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 40% | 1630.14 | 370 / 929 | 0% | 0 | 0 / 0 |
liver | 2% | 23.76 | 5 / 226 | 19% | 1.65 | 78 / 406 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006171 | Biological process | cAMP biosynthetic process |
GO_0007165 | Biological process | signal transduction |
GO_0007608 | Biological process | sensory perception of smell |
GO_0007340 | Biological process | acrosome reaction |
GO_0035556 | Biological process | intracellular signal transduction |
GO_0030317 | Biological process | flagellated sperm motility |
GO_1904322 | Biological process | cellular response to forskolin |
GO_0007189 | Biological process | adenylate cyclase-activating G protein-coupled receptor signaling pathway |
GO_0007338 | Biological process | single fertilization |
GO_0008355 | Biological process | olfactory learning |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0060170 | Cellular component | ciliary membrane |
GO_0005929 | Cellular component | cilium |
GO_0005737 | Cellular component | cytoplasm |
GO_0004016 | Molecular function | adenylate cyclase activity |
GO_0046872 | Molecular function | metal ion binding |
GO_0005524 | Molecular function | ATP binding |
GO_0005516 | Molecular function | calmodulin binding |
Gene name | ADCY3 |
Protein name | Adenylate cyclase type 3 (EC 4.6.1.1) (ATP pyrophosphate-lyase 3) (Adenylate cyclase type III) (AC-III) (Adenylate cyclase, olfactive type) (Adenylyl cyclase 3) (AC3) Adenylate cyclase type 3 (EC 4.6.1.1) adenylate cyclase (EC 4.6.1.1) Adenylate cyclase 3 |
Synonyms | KIAA0511 |
Description | FUNCTION: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Participates in signaling cascades triggered by odorant receptors via its function in cAMP biosynthesis. Required for the perception of odorants. Required for normal sperm motility and normal male fertility. Plays a role in regulating insulin levels and body fat accumulation in response to a high fat diet. . FUNCTION: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. . FUNCTION: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. . |
Accessions | ENST00000427849.5 U3KQ91 U3KQR1 ENST00000498288.1 C9J969 ENST00000438445.1 A0A0A0MSC1 ENST00000679454.1 [O60266-1] O60266 ENST00000260600.9 [O60266-1] B7ZLX9 C9JLX3 ENST00000435135.5 C9JYB5 ENST00000433852.1 ENST00000606682.5 H7C1A6 ENST00000405392.6 |