I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 18% ± 2% | |
| GABAergic neuron | 3 studies | 20% ± 2% | |
| glutamatergic neuron | 3 studies | 25% ± 6% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 18% ± 2% | |
| GABAergic neuron | 3 studies | 20% ± 2% | |
| glutamatergic neuron | 3 studies | 25% ± 6% |
Insufficient scRNA-seq data for expression of ADAT2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1165.24 | 1442 / 1445 | 100% | 5.66 | 183 / 183 |
| prostate | 100% | 1162.59 | 245 / 245 | 99% | 3.55 | 497 / 502 |
| uterus | 100% | 973.06 | 170 / 170 | 99% | 4.69 | 454 / 459 |
| intestine | 100% | 1150.50 | 966 / 966 | 99% | 6.99 | 521 / 527 |
| bladder | 100% | 1054.33 | 21 / 21 | 99% | 5.18 | 498 / 504 |
| lung | 100% | 1350.92 | 578 / 578 | 98% | 4.44 | 1137 / 1155 |
| stomach | 100% | 1114.70 | 359 / 359 | 98% | 6.37 | 279 / 286 |
| pancreas | 100% | 984.33 | 328 / 328 | 97% | 3.29 | 172 / 178 |
| thymus | 100% | 1489.31 | 653 / 653 | 95% | 2.77 | 573 / 605 |
| breast | 100% | 1101.29 | 459 / 459 | 94% | 2.87 | 1046 / 1118 |
| skin | 100% | 1293.72 | 1809 / 1809 | 92% | 3.98 | 432 / 472 |
| adrenal gland | 100% | 1246.86 | 258 / 258 | 90% | 2.10 | 208 / 230 |
| ovary | 100% | 927.52 | 180 / 180 | 89% | 2.60 | 382 / 430 |
| brain | 89% | 497.83 | 2342 / 2642 | 98% | 2.87 | 690 / 705 |
| kidney | 100% | 888.20 | 89 / 89 | 83% | 2.38 | 746 / 901 |
| liver | 100% | 918.43 | 226 / 226 | 71% | 1.72 | 290 / 406 |
| adipose | 100% | 1054.44 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 6.76 | 29 / 29 |
| spleen | 100% | 1623.56 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 3.92 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 3.17 | 1 / 1 |
| blood vessel | 97% | 624.60 | 1300 / 1335 | 0% | 0 | 0 / 0 |
| heart | 85% | 334.97 | 734 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 80% | 2.80 | 64 / 80 |
| muscle | 75% | 294.35 | 599 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 58% | 697.62 | 538 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0002100 | Biological process | tRNA wobble adenosine to inosine editing |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0052717 | Molecular function | tRNA-specific adenosine-34 deaminase activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0008270 | Molecular function | zinc ion binding |
| Gene name | ADAT2 |
| Protein name | tRNA-specific adenosine deaminase 2 (EC 3.5.4.33) (Deaminase domain-containing protein 1) (tRNA-specific adenosine-34 deaminase subunit ADAT2) |
| Synonyms | DEADC1 |
| Description | FUNCTION: Probably participates in deamination of adenosine-34 to inosine in many tRNAs. . |
| Accessions | ENST00000606514.5 [Q7Z6V5-2] ENST00000237283.9 [Q7Z6V5-1] Q7Z6V5 |
