ADAMTS8 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ADAMTS8 at tissue level.

III. Associated gene sets

GO_0008285Biological processnegative regulation of cell population proliferation
GO_0030198Biological processextracellular matrix organization
GO_0006508Biological processproteolysis
GO_0015698Biological processinorganic anion transport
GO_0005576Cellular componentextracellular region
GO_0062023Cellular componentcollagen-containing extracellular matrix
GO_0031012Cellular componentextracellular matrix
GO_0009673Molecular functionlow-affinity phosphate transmembrane transporter activity
GO_0004222Molecular functionmetalloendopeptidase activity
GO_0008201Molecular functionheparin binding
GO_0008270Molecular functionzinc ion binding
GO_0008237Molecular functionmetallopeptidase activity
GO_0005178Molecular functionintegrin binding

IV. Literature review

[source]
Gene nameADAMTS8
Protein nameA disintegrin and metalloproteinase with thrombospondin motifs 8 (ADAM-TS 8) (ADAM-TS8) (ADAMTS-8) (EC 3.4.24.-) (METH-2) (METH-8)
ADAMTS8 protein
SynonymsMETH2
DescriptionFUNCTION: Has anti-angiogenic properties.

AccessionsQ9UP79
Q5FWF1
Q29RW5
ENST00000257359.7