Name | Number of supported studies | Average coverage | |
---|---|---|---|
fibroblast | 7 studies | 25% ± 12% | |
smooth muscle cell | 3 studies | 24% ± 4% |
Insufficient scRNA-seq data for expression of ADAMTS8 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 95% | 1063.04 | 232 / 245 | 96% | 4.95 | 483 / 502 |
brain | 72% | 576.56 | 1893 / 2642 | 96% | 7.10 | 678 / 705 |
lung | 100% | 8302.48 | 576 / 578 | 53% | 3.08 | 616 / 1155 |
esophagus | 92% | 1506.99 | 1326 / 1445 | 44% | 1.62 | 81 / 183 |
bladder | 90% | 1083.43 | 19 / 21 | 40% | 1.67 | 202 / 504 |
intestine | 82% | 1507.43 | 790 / 966 | 48% | 1.66 | 254 / 527 |
stomach | 72% | 1467.66 | 258 / 359 | 56% | 4.22 | 159 / 286 |
uterus | 74% | 516.20 | 126 / 170 | 27% | 3.25 | 125 / 459 |
blood vessel | 85% | 1860.70 | 1136 / 1335 | 0% | 0 | 0 / 0 |
pancreas | 5% | 15.62 | 16 / 328 | 75% | 5.41 | 133 / 178 |
breast | 39% | 215.66 | 180 / 459 | 37% | 1.67 | 416 / 1118 |
ovary | 17% | 100.93 | 30 / 180 | 34% | 1.31 | 147 / 430 |
kidney | 11% | 38.67 | 10 / 89 | 29% | 0.78 | 257 / 901 |
heart | 39% | 275.80 | 333 / 861 | 0% | 0 | 0 / 0 |
thymus | 6% | 24.24 | 40 / 653 | 20% | 0.56 | 123 / 605 |
skin | 7% | 21.70 | 134 / 1809 | 11% | 1.36 | 54 / 472 |
adipose | 18% | 78.96 | 221 / 1204 | 0% | 0 | 0 / 0 |
spleen | 12% | 39.99 | 28 / 241 | 0% | 0 | 0 / 0 |
adrenal gland | 1% | 3.93 | 3 / 258 | 10% | 0.18 | 22 / 230 |
muscle | 5% | 29.65 | 43 / 803 | 0% | 0 | 0 / 0 |
liver | 0% | 0 | 0 / 226 | 5% | 0.09 | 19 / 406 |
eye | 0% | 0 | 0 / 0 | 1% | 0.09 | 1 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0008285 | Biological process | negative regulation of cell population proliferation |
GO_0030198 | Biological process | extracellular matrix organization |
GO_0006508 | Biological process | proteolysis |
GO_0015698 | Biological process | inorganic anion transport |
GO_0005576 | Cellular component | extracellular region |
GO_0062023 | Cellular component | collagen-containing extracellular matrix |
GO_0031012 | Cellular component | extracellular matrix |
GO_0009673 | Molecular function | low-affinity phosphate transmembrane transporter activity |
GO_0004222 | Molecular function | metalloendopeptidase activity |
GO_0008201 | Molecular function | heparin binding |
GO_0008270 | Molecular function | zinc ion binding |
GO_0008237 | Molecular function | metallopeptidase activity |
GO_0005178 | Molecular function | integrin binding |
Gene name | ADAMTS8 |
Protein name | A disintegrin and metalloproteinase with thrombospondin motifs 8 (ADAM-TS 8) (ADAM-TS8) (ADAMTS-8) (EC 3.4.24.-) (METH-2) (METH-8) ADAMTS8 protein |
Synonyms | METH2 |
Description | FUNCTION: Has anti-angiogenic properties. |
Accessions | Q9UP79 Q5FWF1 Q29RW5 ENST00000257359.7 |