ADAMTS7 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ADAMTS7 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ADAMTS7 at tissue level.

III. Associated gene sets

GO_0006029Biological processproteoglycan metabolic process
GO_0071773Biological processcellular response to BMP stimulus
GO_0002062Biological processchondrocyte differentiation
GO_0030198Biological processextracellular matrix organization
GO_0071347Biological processcellular response to interleukin-1
GO_0032331Biological processnegative regulation of chondrocyte differentiation
GO_0071356Biological processcellular response to tumor necrosis factor
GO_0006508Biological processproteolysis
GO_0030199Biological processcollagen fibril organization
GO_0051603Biological processproteolysis involved in protein catabolic process
GO_0043931Biological processossification involved in bone maturation
GO_0005576Cellular componentextracellular region
GO_0031012Cellular componentextracellular matrix
GO_0009986Cellular componentcell surface
GO_0005788Cellular componentendoplasmic reticulum lumen
GO_0008237Molecular functionmetallopeptidase activity
GO_0046872Molecular functionmetal ion binding
GO_0004222Molecular functionmetalloendopeptidase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameADAMTS7
Protein nameA disintegrin and metalloproteinase with thrombospondin motifs 7 (ADAM-TS 7) (ADAM-TS7) (ADAMTS-7) (EC 3.4.24.-) (COMPase)
Synonyms
DescriptionFUNCTION: Metalloprotease that may play a role in the degradation of COMP. .

AccessionsENST00000388820.5
Q9UKP4